The protonation of glycocholate (GC−) and glycodeoxycholate (GDC−) ions was studied at 25°C and in N(CH3)4Cl as an ionic medium at concentrations 0.100, 0.500 and 0.800 mol L−1 by measuring the electromotive force of a galvanic cell containing a glass electrode, as a function of acidity of solution. Also the solubility of glycocholic and glycodeoxycholic acids was determined in the same experimental conditions. The protonation constants of GC− and GDC− were determined and it was found that a further protonation of HGC occurs by increasing acidity. Its protonation constant was also determined.
On the protonation of glycocholate and glycodeoxycholate ions / Bottari, Emilio Giovanni; Festa, Maria Rosa. - In: CHEMICAL SPECIATION AND BIOAVAILABILITY. - ISSN 0954-2299. - STAMPA. - 11 (3):(1999), pp. 77-83. [10.3184/095422999782775654]
On the protonation of glycocholate and glycodeoxycholate ions
BOTTARI, Emilio Giovanni;FESTA, Maria Rosa
1999
Abstract
The protonation of glycocholate (GC−) and glycodeoxycholate (GDC−) ions was studied at 25°C and in N(CH3)4Cl as an ionic medium at concentrations 0.100, 0.500 and 0.800 mol L−1 by measuring the electromotive force of a galvanic cell containing a glass electrode, as a function of acidity of solution. Also the solubility of glycocholic and glycodeoxycholic acids was determined in the same experimental conditions. The protonation constants of GC− and GDC− were determined and it was found that a further protonation of HGC occurs by increasing acidity. Its protonation constant was also determined.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
