Prosthetic joint infections (PJI) are among the most challenging complications of orthopedic surgery, particularly when involving both biofilm-forming low-virulence organisms and multidrug-resistant (MDR) pathogens. This report outlines the complex pathophysiology and clinical challenges associated with PJI, transitioning from a low-grade chronic infection to an acute MDR nosocomial infection, highlighting significant medicolegal implications.
Medico legal aspects on low-grade biofilm infection to MDR nosocomial prosthetic joint infection / Salducci, M., Sofia Simonelli, M., Raimondi, R.. - In: LA CLINICA TERAPEUTICA. - ISSN 1972-6007. - 177:5(2026), pp. 979-981. [10.7417/CT.2026.2093]
Medico legal aspects on low-grade biofilm infection to MDR nosocomial prosthetic joint infection
Mauro Salducci
Primo
Writing – Review & Editing
;
2026
Abstract
Prosthetic joint infections (PJI) are among the most challenging complications of orthopedic surgery, particularly when involving both biofilm-forming low-virulence organisms and multidrug-resistant (MDR) pathogens. This report outlines the complex pathophysiology and clinical challenges associated with PJI, transitioning from a low-grade chronic infection to an acute MDR nosocomial infection, highlighting significant medicolegal implications.| File | Dimensione | Formato | |
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Salducci_Medico legal aspects_2026.pdf
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