This article describes a case of severe hyperleukocytosis in a preterm infant with fetal inflammatory response syndrome (FIRS) associated with funisitis of umbilical cord and intrauterine inflammation. FIRS is a cause of leukocytosis in newborn, as well as leukemoid reaction in 21 trisomy, congenital leukemia, sepsis, and steroid prophylaxis. Inflammatory response syndrome is associated with high mortality, developmental impairment and complications of prematurity like intraventricular hemorrhage, chronic lung disease, periventricular leukomalacia, and sepsis.
Leukemoid Reaction and Preterm Birth: A Case Report of {FIRS} (Fetal Inflammatory Response Syndrome) / Tagliani, Sara; Casadio, Luca; Radice, Caterina; Bruno, Ivana; Piccinini, Giancarlo; Ventresca, Silvia; Zago, Silvia; Suppiej, Agnese; Marchetti, Federico. - In: JOURNAL OF NEONATOLOGY. - ISSN 0973-2179. - 35:4(2021), pp. 249-252. [10.1177/09732179211037858]
Leukemoid Reaction and Preterm Birth: A Case Report of {FIRS} (Fetal Inflammatory Response Syndrome)
Ivana Bruno;Silvia Ventresca;
2021
Abstract
This article describes a case of severe hyperleukocytosis in a preterm infant with fetal inflammatory response syndrome (FIRS) associated with funisitis of umbilical cord and intrauterine inflammation. FIRS is a cause of leukocytosis in newborn, as well as leukemoid reaction in 21 trisomy, congenital leukemia, sepsis, and steroid prophylaxis. Inflammatory response syndrome is associated with high mortality, developmental impairment and complications of prematurity like intraventricular hemorrhage, chronic lung disease, periventricular leukomalacia, and sepsis.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
