We present a new unified graph-based representation of medical data, combining genetic information and medical records of patients with medical knowledge via a unique knowledge graph. This approach allows us to infer meaningful information and explanations that would be unavailable by looking at each data set separately. The systematic use of different databases, managed throughout the built knowledge graph, gives new insights toward a better understanding of oncology medicine. Indeed, we reduce some useful medical tasks to well-known problems in theoretical computer science for which efficient algorithms exist.

Toward a Unified Graph-Based Representation of Medical Data for Precision Oncology Medicine / Belluomo, Davide; Calamoneri, Tiziana; Paesani, Giacomo; Salvo, Ivano. - 15276 LNBI:(2025), pp. 96-110. ( Computational Intelligence methods for Bioinformatics and Biostatistics Benevento, Italia ) [10.1007/978-3-031-89704-7_8].

Toward a Unified Graph-Based Representation of Medical Data for Precision Oncology Medicine

Belluomo, Davide;Calamoneri, Tiziana;Paesani, Giacomo;Salvo, Ivano
2025

Abstract

We present a new unified graph-based representation of medical data, combining genetic information and medical records of patients with medical knowledge via a unique knowledge graph. This approach allows us to infer meaningful information and explanations that would be unavailable by looking at each data set separately. The systematic use of different databases, managed throughout the built knowledge graph, gives new insights toward a better understanding of oncology medicine. Indeed, we reduce some useful medical tasks to well-known problems in theoretical computer science for which efficient algorithms exist.
2025
Computational Intelligence methods for Bioinformatics and Biostatistics
knowledge graph; network medicine; precision oncology medicine
04 Pubblicazione in atti di convegno::04b Atto di convegno in volume
Toward a Unified Graph-Based Representation of Medical Data for Precision Oncology Medicine / Belluomo, Davide; Calamoneri, Tiziana; Paesani, Giacomo; Salvo, Ivano. - 15276 LNBI:(2025), pp. 96-110. ( Computational Intelligence methods for Bioinformatics and Biostatistics Benevento, Italia ) [10.1007/978-3-031-89704-7_8].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1747508
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