L-Arginine is involved in many different biological processes and recent reports indicate that it could also play a crucial role in the coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Herein, we present an updated systematic overview of the current evidence on the functional contribution of L-Arginine in COVID-19, describing its actions on endothelial cells and the immune system and discussing its potential as a therapeutic tool, emerged from recent clinical experimentations.

L-arginine and COVID-19: an update / Adebayo, A; Varzideh, F; Wilson, S; Gambardella, J; Eacobacci, M; Jankauskas, Ss; Donkor, K; Kansakar, U; Trimarco, V; Mone, P; Lombardi, A; Santulli, G.. - In: NUTRIENTS. - ISSN 2072-6643. - 13:11(2021). [10.3390/nu13113951]

L-arginine and COVID-19: an update

Lombardi A;
2021

Abstract

L-Arginine is involved in many different biological processes and recent reports indicate that it could also play a crucial role in the coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Herein, we present an updated systematic overview of the current evidence on the functional contribution of L-Arginine in COVID-19, describing its actions on endothelial cells and the immune system and discussing its potential as a therapeutic tool, emerged from recent clinical experimentations.
2021
covid-19; ros; sars-cov-2; t cells; antiviral therapies; arginine; coronavirus; cytokine storm; endothelium; immune response; immunity; inflammation; nitric oxide; nitrosylation; oxidative stress; viral infections
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
L-arginine and COVID-19: an update / Adebayo, A; Varzideh, F; Wilson, S; Gambardella, J; Eacobacci, M; Jankauskas, Ss; Donkor, K; Kansakar, U; Trimarco, V; Mone, P; Lombardi, A; Santulli, G.. - In: NUTRIENTS. - ISSN 2072-6643. - 13:11(2021). [10.3390/nu13113951]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1746981
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