Background: Fibromyalgia (FM) and chronic migraine (CM), both classified as nociplastic pain disorders, significantly impair daily functioning and psychological well-being. These conditions frequently co-occur, forming a comorbid entity termed "Fibromig." Despite their high comorbidity (45–80%), little research has focused on the combined psychological manifestations of Fibromig. Objectives: This study aimed to compare psychopathological symptoms (somatization, depression, anxiety, obsessive-compulsive tendencies, interpersonal sensitivity, hostility, phobic anxiety, paranoid ideation, and psychoticism) and quality of life (QoL) in women diagnosed with FM, CM, and Fibromig. We hypothesized that the Fibromig group would exhibit higher scores on psychopathological measures and report poorer mental health outcomes compared to FM or CM alone. Methods: Data were collected from 295 women across three hospitals in Italy. Psychopathological symptoms were assessed using validated tools, including the Symptom Checklist-90-Revised, the General Anxiety Disorder Scale, the Hamilton Depression Rating Scale, and the Short Form-12 for QoL evaluation. Results: The Kruskal-Wallis test revealed significant differences across all measures (p < .001–.004). Fibromig and FM groups reported more severe psychopathological symptoms than the CM group, particularly in depression, anxiety, obsessive-compulsive tendencies, interpersonal sensitivity, hostility, phobic anxiety, paranoid ideation, and psychoticism. Somatization was significantly higher in Fibromig than in FM or CM. Both FM and Fibromig groups showed more compromised physical and mental QoL. Conclusion: Psychopathological symptoms are prevalent in CM, FM and particularly Fibromig, highlighting the need for mental health interventions alongside clinical management. Early psychological care may mitigate the impact of these symptoms on disease progression and patient outcomes.
Psychopathological and Quality of Life Burdens in Fibromyalgia, Chronic Migraine, and Their Comorbidity (Fibromig) / Nimbi, F. M.; Bottiroli, S.; Castelli, L.; Cavicchioli, M.; Benfante, A.; Cangelosi, M.; Mesce, M.; Torelli, A.; Iannuccelli, C.; Franco, Di; Sarzi-Puttini, P.; Galli, F.. - (2025). ( The 7th International Congress on Controversies in Fibromyalgia Vienna ).
Psychopathological and Quality of Life Burdens in Fibromyalgia, Chronic Migraine, and Their Comorbidity (Fibromig)
Nimbi F. M.;Cavicchioli M.;Mesce M.;Torelli A.;Iannuccelli C.;Di Franco;Galli, F.
2025
Abstract
Background: Fibromyalgia (FM) and chronic migraine (CM), both classified as nociplastic pain disorders, significantly impair daily functioning and psychological well-being. These conditions frequently co-occur, forming a comorbid entity termed "Fibromig." Despite their high comorbidity (45–80%), little research has focused on the combined psychological manifestations of Fibromig. Objectives: This study aimed to compare psychopathological symptoms (somatization, depression, anxiety, obsessive-compulsive tendencies, interpersonal sensitivity, hostility, phobic anxiety, paranoid ideation, and psychoticism) and quality of life (QoL) in women diagnosed with FM, CM, and Fibromig. We hypothesized that the Fibromig group would exhibit higher scores on psychopathological measures and report poorer mental health outcomes compared to FM or CM alone. Methods: Data were collected from 295 women across three hospitals in Italy. Psychopathological symptoms were assessed using validated tools, including the Symptom Checklist-90-Revised, the General Anxiety Disorder Scale, the Hamilton Depression Rating Scale, and the Short Form-12 for QoL evaluation. Results: The Kruskal-Wallis test revealed significant differences across all measures (p < .001–.004). Fibromig and FM groups reported more severe psychopathological symptoms than the CM group, particularly in depression, anxiety, obsessive-compulsive tendencies, interpersonal sensitivity, hostility, phobic anxiety, paranoid ideation, and psychoticism. Somatization was significantly higher in Fibromig than in FM or CM. Both FM and Fibromig groups showed more compromised physical and mental QoL. Conclusion: Psychopathological symptoms are prevalent in CM, FM and particularly Fibromig, highlighting the need for mental health interventions alongside clinical management. Early psychological care may mitigate the impact of these symptoms on disease progression and patient outcomes.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
