Recent pandemic stressed out the necessity to develop new and efficient biosensor system for the detection of airborne pathogens. A new, simple strategy is presented for the optical biosensing of airborne pathogens employing vibrational spectroscopy interrogation and nanostructured platforms. As a proof of concept, we pay attention to SARS-Cov-2 virus, using its spike glycoprotein as optical biomarker. Here, we report the main steps in the optical biosensor development, from the vibrational characterization of biomarker and its structural investigation to the potential nanostructured substrates. These results constitute only the preliminary first steps anyway, the suggested approach could represent a prospective label-free promising tool for a wide range monitoring of pathogens in air in close environments.
Optical Infrared biosensing for ultrasensitive monitoring of SARS-CoV-2 variants / Mosetti, Rosanna; Mancini, Tiziana; D’Arco, Annalisa; Macis, Salvatore; Luchetti, Nicole; Minicozzi, Velia; Notargiacomo, Andrea; Pea, Marialilia; Falcaro, Paolo; Carraro, Francesco; DELLA VENTURA, Giancarlo; Marcelli and Stefano Lupi, Augusto. - (2024). (Intervento presentato al convegno EOSAM2024 European Optical Society Annual Meeting tenutosi a Napoli).
Optical Infrared biosensing for ultrasensitive monitoring of SARS-CoV-2 variants
Rosanna MosettiPrimo
;Tiziana Mancini;Annalisa D’Arco;Salvatore Macis;Andrea Notargiacomo;Giancarlo Della Ventura;
2024
Abstract
Recent pandemic stressed out the necessity to develop new and efficient biosensor system for the detection of airborne pathogens. A new, simple strategy is presented for the optical biosensing of airborne pathogens employing vibrational spectroscopy interrogation and nanostructured platforms. As a proof of concept, we pay attention to SARS-Cov-2 virus, using its spike glycoprotein as optical biomarker. Here, we report the main steps in the optical biosensor development, from the vibrational characterization of biomarker and its structural investigation to the potential nanostructured substrates. These results constitute only the preliminary first steps anyway, the suggested approach could represent a prospective label-free promising tool for a wide range monitoring of pathogens in air in close environments.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.