Drug-Induced Versus Eosinophilic Esophagitis: A Challenging Case Report

We describe a challenging case of differential diagnosis between drug-induced esophagitis (DIE) and eosinophilic esophagitis (EoE). DIE is an uncommon cause of esophagitis induced by some categories of drugs that must be taken into consideration when the patient’s history does not fully match with EoE. DIE and EoE, although have similar clinical, endoscopic, and even histological features, do not share the same treatment. This case highlights the importance of collecting an accurate medical history and adequate esophageal biopsy sampling during endoscopy to avoid errors with therapeutic implications.