Leptomeningeal carcinomatosis (LC) is a rare site of metastasis in solid tumors, and it is associated with poor prognosis due to disabling symptoms and a scarcity of treatment options. This condition is an uncommon entity in gastric cancer (GC). We present a case of primary LC manifestation in a patient with an incidental diagnosis of localized node-negative GC. We additionally perform a literature review and discuss the diagnostic and therapeutic challenges. In conclusion, LC from GC represents a rare condition with a dramatic prognosis. Its diagnosis might be very challenging. A multidisciplinary approach appears to be the best strategy for the management of LC from GC.
Leptomeningeal Carcinomatosis in Early Gastric Cancer: A Case Report and Literature Review / Lucarini, Alessio; Arrivi, Giulia; Liotta, Elena; Li Causi, Francesco Saverio; Di Cicco, Leonardo; Mazzuca, Federica; Osti, Mattia Falchetto; Balducci, Genoveffa; Mercantini, Paolo. - In: HEALTHCARE. - ISSN 2227-9032. - 12:12(2024). [10.3390/healthcare12121184]
Leptomeningeal Carcinomatosis in Early Gastric Cancer: A Case Report and Literature Review
Alessio Lucarini
Conceptualization
;giulia arriviConceptualization
;Elena LiottaWriting – Original Draft Preparation
;Francesco Saverio Li CausiResources
;Leonardo Di CiccoWriting – Original Draft Preparation
;Federica MazzucaWriting – Review & Editing
;Mattia Falchetto OSTIWriting – Review & Editing
;Genoveffa BalducciSupervision
;Paolo MercantiniSupervision
2024
Abstract
Leptomeningeal carcinomatosis (LC) is a rare site of metastasis in solid tumors, and it is associated with poor prognosis due to disabling symptoms and a scarcity of treatment options. This condition is an uncommon entity in gastric cancer (GC). We present a case of primary LC manifestation in a patient with an incidental diagnosis of localized node-negative GC. We additionally perform a literature review and discuss the diagnostic and therapeutic challenges. In conclusion, LC from GC represents a rare condition with a dramatic prognosis. Its diagnosis might be very challenging. A multidisciplinary approach appears to be the best strategy for the management of LC from GC.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
