Introduction: We report a case and discuss the clinical characteristics and treatment of spontaneous Descemet membrane detachment (DMD). Case description: We describe a rare case of spontaneous DMD in a patient with prior anterior uveitis and provide a review of the current literature. A 20-year-old woman with a prior history of anterior uveitis presented with vision loss in the left eye. The slit-lamp examination showed corneal edema secondary to DMD, confirmed by anterior segment optical coherence tomography (AS-OCT). The patient underwent an intracameral injection of 20% sulphur hexafluoride (SF6) with complete resolution of the DMD. Although rare, several cases of spontaneous DMD have been reported in the literature, mostly occurring after intraocular surgery. We searched the Pubmed database (1949-2021) for peer-reviewed publications relevant to the topic of spontaneous DMD. Discussion: The pathogenesis of spontaneous DMD is complex and depends on several factors. It can occur due to anatomical anomalies, inflammatory disease, trauma, chemical injuries, and surgical or laser procedures. In most cases, early diagnosis and appropriate management led to resolution.

Case report: “spontaneous descemet membrane detachment” / Moramarco, Antonio; Iannetta, Danilo; Cimino, Luca; Romano, Vito; Gardini, Lorenzo; Fontana, Luigi. - In: JOURNAL OF CLINICAL MEDICINE. - ISSN 2077-0383. - 12:1(2022), pp. 1-7. [10.3390/jcm12010330]

Case report: “spontaneous descemet membrane detachment”

Iannetta, Danilo
Secondo
Conceptualization
;
2022

Abstract

Introduction: We report a case and discuss the clinical characteristics and treatment of spontaneous Descemet membrane detachment (DMD). Case description: We describe a rare case of spontaneous DMD in a patient with prior anterior uveitis and provide a review of the current literature. A 20-year-old woman with a prior history of anterior uveitis presented with vision loss in the left eye. The slit-lamp examination showed corneal edema secondary to DMD, confirmed by anterior segment optical coherence tomography (AS-OCT). The patient underwent an intracameral injection of 20% sulphur hexafluoride (SF6) with complete resolution of the DMD. Although rare, several cases of spontaneous DMD have been reported in the literature, mostly occurring after intraocular surgery. We searched the Pubmed database (1949-2021) for peer-reviewed publications relevant to the topic of spontaneous DMD. Discussion: The pathogenesis of spontaneous DMD is complex and depends on several factors. It can occur due to anatomical anomalies, inflammatory disease, trauma, chemical injuries, and surgical or laser procedures. In most cases, early diagnosis and appropriate management led to resolution.
2022
Descemet membrane detachment; anterior segment optical coherence tomography; anterior uveitis; corneal edema; sulphur hexafluoride
01 Pubblicazione su rivista::01i Case report
Case report: “spontaneous descemet membrane detachment” / Moramarco, Antonio; Iannetta, Danilo; Cimino, Luca; Romano, Vito; Gardini, Lorenzo; Fontana, Luigi. - In: JOURNAL OF CLINICAL MEDICINE. - ISSN 2077-0383. - 12:1(2022), pp. 1-7. [10.3390/jcm12010330]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1710940
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