The SMART-BREED project aims to develop innovative molecular technologies to study the effects of genetic variability and use this information to accelerate the breeding of new resilient varieties that maintain their productive and typical characteristics in more variable and extreme environmental conditions. Genetic diversity, in natural or domesticated populations, constitutes a source of allelic variants "tested" naturally in the field of evolution, and are therefore an important resource for genetic improvement. More than 60% of adaptive mutations are associated with genes encoding transcription factors (TF), which constitute the main target genes on which the process of adaptation acts in wild and domesticated plant populations. As a "proof of concept", the project focuses on target transcription factors with a proven role in plant architecture traits that are important for the production and adaptation of horticultural species: transition to flowering, leaf development and shade avoidance. Knowledge from Arabidopsis is being translated in Lactuca sativa as a model for Asteraceae and Solanum lycopersicum as a model for Solanaceae. Three technological platforms (genetic diversity, genome editing and gene co-expression networks) are being integrated to design new molecular strategies of genetic improvement based on a candidate gene approach, that could potentially extend to any candidate TF and agronomical trait.
The “SMART-BREED” Project: innovative molecular technologies to accelerate adaptation of horticultural species / Frugis, Giovanna; Augelletti, Floriana; Baima, Simona; Brozzi, Ilaria; Carabelli, Monica; D'Attilia, Chiara; Del Bufalo, Alessandro; De Luca, Vanessa; DI PINTO, Alberico; D'Orso, Fabio; Chiatti, Valeria; Fabriani, Marco; Felici, Barbara; Forte, Valentina; Gentile, Davide; Adelaide lannelli, Maria; Lori, Valentina; Morelli, Giorgio; Possenti, Marco; Samperna, Simone; Sessa, Giovanna. - (2023). (Intervento presentato al convegno VIB Translational Research in Crops tenutosi a Ghent (Belgium)).
The “SMART-BREED” Project: innovative molecular technologies to accelerate adaptation of horticultural species.
Alberico Di Pinto;Fabio D'Orso;Valentina Forte;Davide Gentile;Giorgio Morelli;
2023
Abstract
The SMART-BREED project aims to develop innovative molecular technologies to study the effects of genetic variability and use this information to accelerate the breeding of new resilient varieties that maintain their productive and typical characteristics in more variable and extreme environmental conditions. Genetic diversity, in natural or domesticated populations, constitutes a source of allelic variants "tested" naturally in the field of evolution, and are therefore an important resource for genetic improvement. More than 60% of adaptive mutations are associated with genes encoding transcription factors (TF), which constitute the main target genes on which the process of adaptation acts in wild and domesticated plant populations. As a "proof of concept", the project focuses on target transcription factors with a proven role in plant architecture traits that are important for the production and adaptation of horticultural species: transition to flowering, leaf development and shade avoidance. Knowledge from Arabidopsis is being translated in Lactuca sativa as a model for Asteraceae and Solanum lycopersicum as a model for Solanaceae. Three technological platforms (genetic diversity, genome editing and gene co-expression networks) are being integrated to design new molecular strategies of genetic improvement based on a candidate gene approach, that could potentially extend to any candidate TF and agronomical trait.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
