Necrolytic migratory erythema impact on prognosis and diagnosis of glucagonoma: a case report

Glucagonoma is a well-differentiated slowly proliferating pancreatic neuroendocrine tumor, characterized by variable manifestations related to glucagon excess. Glucagonoma syndrome is a rare neuroendocrine tumor-related syndrome, characterized by a frequent and early cutaneous manifestation, the necrolytic migratory erythema, along with variable systemic involvement. We present a case of a 51-year-old female diagnosed with glucagonoma, highlighting the clinical features, diagnostic approach, and management strategies. Early recognition of the necrolytic migratory erythema and multidisciplinary care of the syndrome are crucial for optimizing outcomes in affected patients.