Cushing's syndrome (CS) is characterized by a series of systemic complications that increase cardiovascular risk and cause severe atherosclerotic damage that develops in parallel with an acquired metabolic syndrome. Short-term remission from hypercortisolism improves metabolic and vascular damages, but long-term remission from CS seems to be associated with similar or worse metabolic and vascular damage, probably because of persistent abdominal obesity or insulin resistance years after normalization of cortisol secretion. Study results suggest that an increased cardiovascular risk also may persist in patients who undergo treatment with exogenous glucocorticoids after therapy withdrawal. Considering the many patients subjected to corticosteroid treatment, this could be of great clinical relevance and should be investigated thoroughly.

The metabolic syndrome and cardiovascular risk in Cushing's syndrome / Pivonello, Rosario; Faggiano, Antongiulio; Lombardi, Gaetano; Colao, Annamaria. - In: ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA. - ISSN 0889-8529. - 34:2(2005), p. 327. [10.1016/j.ecl.2005.01.010]

The metabolic syndrome and cardiovascular risk in Cushing's syndrome

Pivonello, Rosario;Faggiano, Antongiulio;
2005

Abstract

Cushing's syndrome (CS) is characterized by a series of systemic complications that increase cardiovascular risk and cause severe atherosclerotic damage that develops in parallel with an acquired metabolic syndrome. Short-term remission from hypercortisolism improves metabolic and vascular damages, but long-term remission from CS seems to be associated with similar or worse metabolic and vascular damage, probably because of persistent abdominal obesity or insulin resistance years after normalization of cortisol secretion. Study results suggest that an increased cardiovascular risk also may persist in patients who undergo treatment with exogenous glucocorticoids after therapy withdrawal. Considering the many patients subjected to corticosteroid treatment, this could be of great clinical relevance and should be investigated thoroughly.
2005
MEN1;
01 Pubblicazione su rivista::01i Case report
The metabolic syndrome and cardiovascular risk in Cushing's syndrome / Pivonello, Rosario; Faggiano, Antongiulio; Lombardi, Gaetano; Colao, Annamaria. - In: ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA. - ISSN 0889-8529. - 34:2(2005), p. 327. [10.1016/j.ecl.2005.01.010]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1675398
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 37
  • Scopus 153
  • ???jsp.display-item.citation.isi??? 135
social impact