cutely decompensated chronic heart failure (adCHF) is among the most important causes of in-hospital mortality. R-wave peak time (RpT) or delayed intrinsicoid deflection was proposed as a risk marker of sudden cardiac death and heart failure decompensation. Authors want to verify if QR interval or RpT, obtained from 12-lead standard ECG and during 5-min ECG recordings (II lead), could be useful to identify adCHF. At hospital admission, patients underwent 5-min ECG recordings, obtaining mean and standard deviation (SD) of the following ECG intervals: QR, QRS, QT, JT, and T peak–T end (Te). The RpT from a standard ECG was calculated. Patients were grouped by the age-stratified Januzzi NT-proBNP cut-off. A total of 140 patients with suspected adCHF were enrolled: 87 (mean age 83 ± 10, M/F 38/49) with and 53 (mean age: 83 ± 9, M/F: 23/30) without adCHF. V5-, V6- (p < 0.05) RpT, and QRSD, QRSSD, QTSD, JTSD, and TeSD p < 0.001 were significantly higher in the adCHF group. Multivariable logistic regression analysis demonstrated that the mean of QT (p < 0.05) and Te (p < 0.05) were the most reliable markers of in-hospital mortality. V6 RpT was directly related to NT-proBNP (r: 0.26, p < 0.001) and inversely related to a left ventricular ejection fraction (r: 0.38, p < 0.001). The intrinsicoid deflection time (obtained from V5-6 and QRSD) could be used as a possible marker of adCHF.

Electrocardiographic and other noninvasive hemodynamic markers in decompensated CHF patients / Piccirillo, Gianfranco; Moscucci, Federica; Mezzadri, Martina; Caltabiano, Cristina; DI DIEGO, Ilaria; Carnovale, Myriam; Corrao, Andrea; Stefano, Sara; Scinicariello, Claudia; Giuffre', Marco; De Santis, Valerio; Sciomer, Susanna; Rossi, Pietro; Magri', Damiano. - In: JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE. - ISSN 2308-3425. - 10:3(2023). [10.3390/jcdd10030125]

Electrocardiographic and other noninvasive hemodynamic markers in decompensated CHF patients

Gianfranco Piccirillo;Federica Moscucci
;
Martina Mezzadri;Cristina Caltabiano;Ilaria Di Diego;Myriam Carnovale;Andrea Corrao;Sara Stefano;Claudia Scinicariello;Marco Giuffre';Valerio De Santis;Susanna Sciomer;Damiano Magri
2023

Abstract

cutely decompensated chronic heart failure (adCHF) is among the most important causes of in-hospital mortality. R-wave peak time (RpT) or delayed intrinsicoid deflection was proposed as a risk marker of sudden cardiac death and heart failure decompensation. Authors want to verify if QR interval or RpT, obtained from 12-lead standard ECG and during 5-min ECG recordings (II lead), could be useful to identify adCHF. At hospital admission, patients underwent 5-min ECG recordings, obtaining mean and standard deviation (SD) of the following ECG intervals: QR, QRS, QT, JT, and T peak–T end (Te). The RpT from a standard ECG was calculated. Patients were grouped by the age-stratified Januzzi NT-proBNP cut-off. A total of 140 patients with suspected adCHF were enrolled: 87 (mean age 83 ± 10, M/F 38/49) with and 53 (mean age: 83 ± 9, M/F: 23/30) without adCHF. V5-, V6- (p < 0.05) RpT, and QRSD, QRSSD, QTSD, JTSD, and TeSD p < 0.001 were significantly higher in the adCHF group. Multivariable logistic regression analysis demonstrated that the mean of QT (p < 0.05) and Te (p < 0.05) were the most reliable markers of in-hospital mortality. V6 RpT was directly related to NT-proBNP (r: 0.26, p < 0.001) and inversely related to a left ventricular ejection fraction (r: 0.38, p < 0.001). The intrinsicoid deflection time (obtained from V5-6 and QRSD) could be used as a possible marker of adCHF.
2023
acutely decompensated chronic heart failure; intrinsicoid deflection time; ECG markers; tele-monitoring; prevention
01 Pubblicazione su rivista::01a Articolo in rivista
Electrocardiographic and other noninvasive hemodynamic markers in decompensated CHF patients / Piccirillo, Gianfranco; Moscucci, Federica; Mezzadri, Martina; Caltabiano, Cristina; DI DIEGO, Ilaria; Carnovale, Myriam; Corrao, Andrea; Stefano, Sara; Scinicariello, Claudia; Giuffre', Marco; De Santis, Valerio; Sciomer, Susanna; Rossi, Pietro; Magri', Damiano. - In: JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE. - ISSN 2308-3425. - 10:3(2023). [10.3390/jcdd10030125]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1674528
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