Genetic and structural analyses here presented do not provide evidence for a particularly high risk of XBB.1.5 expansion to become a new, global public health threat. The Omicron variant of concern, and more specifically BA.5 and its descendant lineages, remain the dominant variants circulating globally [4]. The variant XBB.1.5 appears to spread even more slowly than the last sub-variants that have caused concerns in 2022. However, it cannot be excluded that new mutations will occur and make XBB.1.5 more dangerous. In this context, extensive genome-based monitoring must continue uninterruptedly because it is the only way to identify and/or predict important changes in the genomic composition of SARS-CoV-2.
Genetic and structural genome-based survey reveals the low potential for epidemiological expansion of the SARS-CoV-2 XBB.1.5 sublineage / Scarpa, F., Imperia, E., Azzena, I., Giovanetti, M., Benvenuto, D., Locci, C., Casu, M., Fiori, P.L., Maruotti, A., Ceccarelli, G., Borsetti, A., Caruso, A., Cauda, R., Cassone, A., Via, A., Pascarella, S., Sanna, D., Ciccozzi, M.. - In: JOURNAL OF INFECTION. - ISSN 0163-4453. - (2023). [10.1016/j.jinf.2023.02.039]
Genetic and structural genome-based survey reveals the low potential for epidemiological expansion of the SARS-CoV-2 XBB.1.5 sublineage
Via, Allegra;Pascarella, Stefano;
2023
Abstract
Genetic and structural analyses here presented do not provide evidence for a particularly high risk of XBB.1.5 expansion to become a new, global public health threat. The Omicron variant of concern, and more specifically BA.5 and its descendant lineages, remain the dominant variants circulating globally [4]. The variant XBB.1.5 appears to spread even more slowly than the last sub-variants that have caused concerns in 2022. However, it cannot be excluded that new mutations will occur and make XBB.1.5 more dangerous. In this context, extensive genome-based monitoring must continue uninterruptedly because it is the only way to identify and/or predict important changes in the genomic composition of SARS-CoV-2.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
