Constitutive heterochromatin represents a significant fraction of eukaryotic genomes (10% in Arabidopsis, 20% in humans, 30% in D. melanogaster, and up to 85% in certain nematodes) and shares similar genetic and molecular properties in animal and plant species. Studies conducted over the last few years on D. melanogaster and other organisms led to the discovery of several functions associated with constitutive heterochromatin. This made it possible to revise the concept that this ubiquitous genomic territory is incompatible with gene expression. The aim of this review is to focus the attention on a group of protein-coding genes resident in D. melanogaster constitutive of heterochromatin, which are implicated in different steps of cell division.

The green valley of Drosophila melanogaster constitutive heterochromatin: protein-coding genes involved in cell division control / Messina, Giovanni; Prozzillo, Yuri; Bizzochi, Greta; Massimiliano Marsano, Renè; Dimitri, Patrizio. - In: CELLS. - ISSN 2073-4409. - 11:19(2022). [10.3390/cells11193058]

The green valley of Drosophila melanogaster constitutive heterochromatin: protein-coding genes involved in cell division control

Giovanni Messina
Co-primo
;
Yuri Prozzillo
Co-primo
;
Patrizio Dimitri
Ultimo
2022

Abstract

Constitutive heterochromatin represents a significant fraction of eukaryotic genomes (10% in Arabidopsis, 20% in humans, 30% in D. melanogaster, and up to 85% in certain nematodes) and shares similar genetic and molecular properties in animal and plant species. Studies conducted over the last few years on D. melanogaster and other organisms led to the discovery of several functions associated with constitutive heterochromatin. This made it possible to revise the concept that this ubiquitous genomic territory is incompatible with gene expression. The aim of this review is to focus the attention on a group of protein-coding genes resident in D. melanogaster constitutive of heterochromatin, which are implicated in different steps of cell division.
2022
constitutive heterochromatin; heterochromatic genes; drosophila; mitotic apparatus; cell division
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
The green valley of Drosophila melanogaster constitutive heterochromatin: protein-coding genes involved in cell division control / Messina, Giovanni; Prozzillo, Yuri; Bizzochi, Greta; Massimiliano Marsano, Renè; Dimitri, Patrizio. - In: CELLS. - ISSN 2073-4409. - 11:19(2022). [10.3390/cells11193058]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1656716
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