Prokineticin-2 (PK2) is a chemokine-like peptide abundantly expressed in the central nervous system (CNS), involved in multiple physiological and pathological conditions, which acts as an insult-inducible endangering mediator contributing to cellular defence.1 Of relevance, PK2 is highly induced during early phases of dopaminergic degeneration in Parkinson’s disease (PD), activating a neuroprotective response by the PGC-1αmediated restoration of mitochondrial function

Increase of Prokineticin-2 in Serum of Patients with Parkinson's Disease / Schirinzi, T.; Maftei, D.; Pieri, M.; Bernardini, S.; Mercuri, N. B.; Lattanzi, R.; Severini, C.. - In: MOVEMENT DISORDERS. - ISSN 0885-3185. - 36:4(2021), pp. 1031-1033. [10.1002/mds.28458]

Increase of Prokineticin-2 in Serum of Patients with Parkinson's Disease

Maftei D.
Methodology
;
Lattanzi R.
Conceptualization
;
2021

Abstract

Prokineticin-2 (PK2) is a chemokine-like peptide abundantly expressed in the central nervous system (CNS), involved in multiple physiological and pathological conditions, which acts as an insult-inducible endangering mediator contributing to cellular defence.1 Of relevance, PK2 is highly induced during early phases of dopaminergic degeneration in Parkinson’s disease (PD), activating a neuroprotective response by the PGC-1αmediated restoration of mitochondrial function
2021
biomarkers; chemokine; neuroinflammation; Parkinson's disease; prokineticin 2; Biomarkers; Humans; Inflammation; Parkinson Disease
01 Pubblicazione su rivista::01a Articolo in rivista
Increase of Prokineticin-2 in Serum of Patients with Parkinson's Disease / Schirinzi, T.; Maftei, D.; Pieri, M.; Bernardini, S.; Mercuri, N. B.; Lattanzi, R.; Severini, C.. - In: MOVEMENT DISORDERS. - ISSN 0885-3185. - 36:4(2021), pp. 1031-1033. [10.1002/mds.28458]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1643896
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