Immune checkpoint inhibitors (ICIs) have shown promise in treating cancer patients and Pembrolizumab is a monoclonal IgG4 antibody that targets a human cell surface protein (receptor) called PD-1. Among the side effects a rare cranial nerve palsy unrelated to the surgical treatment may occur. We report a case of a woman, which after neurosurgical treatment for cerebellar metastasis presented painless third cranial nerve palsy. Informed consent was obtained from the patient for the publication of this report.

Third Cranial Nerve Palsy after Monoclonal Antibody Therapy for Lung Cancer: A Case Report / Missori, Paolo; Ambrosone, Angela; Cristofani, Leonardo; Fattapposta, Francesco; Curra', Antonio. - In: CASE REPORTS IN OPHTHALMOLOGY. - ISSN 1663-2699. - (2022), pp. 282-285. [10.1159/000524114]

Third Cranial Nerve Palsy after Monoclonal Antibody Therapy for Lung Cancer: A Case Report

Paolo Missori
Primo
Writing – Review & Editing
;
Angela Ambrosone
Membro del Collaboration Group
;
Leonardo Cristofani
Membro del Collaboration Group
;
Francesco Fattapposta
Supervision
;
Antonio Currà
Ultimo
Writing – Review & Editing
2022

Abstract

Immune checkpoint inhibitors (ICIs) have shown promise in treating cancer patients and Pembrolizumab is a monoclonal IgG4 antibody that targets a human cell surface protein (receptor) called PD-1. Among the side effects a rare cranial nerve palsy unrelated to the surgical treatment may occur. We report a case of a woman, which after neurosurgical treatment for cerebellar metastasis presented painless third cranial nerve palsy. Informed consent was obtained from the patient for the publication of this report.
2022
cancer; cranial nerve; lung; metastasis; Pembrolizumab; side effects
01 Pubblicazione su rivista::01i Case report
Third Cranial Nerve Palsy after Monoclonal Antibody Therapy for Lung Cancer: A Case Report / Missori, Paolo; Ambrosone, Angela; Cristofani, Leonardo; Fattapposta, Francesco; Curra', Antonio. - In: CASE REPORTS IN OPHTHALMOLOGY. - ISSN 1663-2699. - (2022), pp. 282-285. [10.1159/000524114]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1637804
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