In the present study, we successfully synthesized N-doped carbon quantum dots (N-CQDs) using a top-down approach, i.e., hydroxyl radical opening of fullerene with hydrogen peroxide, in basic ambient using ammonia for two different reaction times. The ensuing characterization via dynamic light scattering, SEM, and IR spectroscopy revealed a size control that was dependent on the reaction time, as well as a more pronounced-NH2 functionalization. The N-CQDs were probed for metal ion detection in aqueous solutions and during bioimaging and displayed a Cr3+ and Cu2+ selectivity shift at a higher degree of-NH2 functionalization, as well as HEK-293 cell nuclei marking.

Top-down n-doped carbon quantum dots for multiple purposes: Heavy metal detection and intracellular fluorescence / Limosani, F.; Bauer, E. M.; Cecchetti, D.; Biagioni, S.; Orlando, V.; Pizzoferrato, R.; Prosposito, P.; Carbone, M.. - In: NANOMATERIALS. - ISSN 2079-4991. - 11:9(2021). [10.3390/nano11092249]

Top-down n-doped carbon quantum dots for multiple purposes: Heavy metal detection and intracellular fluorescence

Biagioni S.;Orlando V.;
2021

Abstract

In the present study, we successfully synthesized N-doped carbon quantum dots (N-CQDs) using a top-down approach, i.e., hydroxyl radical opening of fullerene with hydrogen peroxide, in basic ambient using ammonia for two different reaction times. The ensuing characterization via dynamic light scattering, SEM, and IR spectroscopy revealed a size control that was dependent on the reaction time, as well as a more pronounced-NH2 functionalization. The N-CQDs were probed for metal ion detection in aqueous solutions and during bioimaging and displayed a Cr3+ and Cu2+ selectivity shift at a higher degree of-NH2 functionalization, as well as HEK-293 cell nuclei marking.
2021
Bioimaging; Carbon quantum dots; Fullerene; Heavy metals; Photoluminescence; Quench-ing; Spectroscopy
01 Pubblicazione su rivista::01a Articolo in rivista
Top-down n-doped carbon quantum dots for multiple purposes: Heavy metal detection and intracellular fluorescence / Limosani, F.; Bauer, E. M.; Cecchetti, D.; Biagioni, S.; Orlando, V.; Pizzoferrato, R.; Prosposito, P.; Carbone, M.. - In: NANOMATERIALS. - ISSN 2079-4991. - 11:9(2021). [10.3390/nano11092249]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1636537
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