Only 0.3–1% of laryngeal cancer are non-squamous cell neoplasms. Of these, a rare entity is inflammatory myofibroblastic tumour (IMT), in which anaplastic lymphoma kinase-1 (ALK-1) is frequently expressed. Just 50 cases of IMT have been reported. Therefore, many otolaryngologists may be unfamiliar with this type of tumour and be prone to its over- or undertreatment. We report a case of ALK-1–negative IMT treated with transoral endoscopic excision and disease-free 6 months after surgery.
Inflammatory myofibroblastic tumour of the larynx: report of a case / Colizza, Andrea; Meliante, PIERO GIUSEPPE; Donsante, Samantha; Riminucci, Mara; Greco, Antonio; DE VINCENTIIS, Marco; Corsi, Alessandro. - In: EAR, NOSE & THROAT JOURNAL. - ISSN 0145-5613. - (2022), p. 014556132211010. [10.1177/01455613221101087]
Inflammatory myofibroblastic tumour of the larynx: report of a case
Andrea Colizza
Primo
;Piero Giuseppe MelianteSecondo
;Samantha Donsante;Mara Riminucci;Antonio Greco;Marco De VincentiisPenultimo
;Alessandro CorsiUltimo
2022
Abstract
Only 0.3–1% of laryngeal cancer are non-squamous cell neoplasms. Of these, a rare entity is inflammatory myofibroblastic tumour (IMT), in which anaplastic lymphoma kinase-1 (ALK-1) is frequently expressed. Just 50 cases of IMT have been reported. Therefore, many otolaryngologists may be unfamiliar with this type of tumour and be prone to its over- or undertreatment. We report a case of ALK-1–negative IMT treated with transoral endoscopic excision and disease-free 6 months after surgery.| File | Dimensione | Formato | |
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Colizza_Inflammatory myofibroblastic tumour_2022.pdf
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Note: https://journals.sagepub.com/doi/full/10.1177/01455613221101087
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