A 31-year-old man was referred to an adult urologist for a renal polar mass that measured 7.2 cm in maximum diameter. Robotic assisted complete tumor excision for suspicious renal cell carcinoma was carried out, preserving the rest of the left kidney. Histopathology showed a Wilms tumor (WT) with positive margins. No postoperative therapy was made, and the patient shortly presented an abdominal recurrence. The patient was referred to our pediatric oncology unit; he received preoperative chemotherapy, followed by surgery (completion nephrectomy and removal of neoplastic deposits in the omentum and parietal peritoneum), postoperative chemotherapy, and abdomen radiotherapy. He is well at the 5-year follow-up. Peritoneal dissemination after laparoscopic nephron-sparing surgery (NSS) in a child with a 10-cm WT was previously reported. We suggest open NSS for large WT may be safer than laparoscopic or robotic NSS because carbon dioxide pneumoperitoneum and traumatic handling of tumor may predispose to tumor cell migration. An abdominal WT relapse in adults can be salvaged by multimodal therapy recommended by current pediatric WT guidelines.

Abdominal recurrence after robotic nephron-sparing surgery for Wilms tumor in an adult patient / Schiavetti, Amalia; Ferrara, Eva; De Grazia, Alessandra; Cozzi, Denis A. - In: UROLOGIA INTERNATIONALIS. - ISSN 1423-0399. - (2021), pp. 1-4. [10.1159/000514595]

Abdominal recurrence after robotic nephron-sparing surgery for Wilms tumor in an adult patient

Schiavetti, Amalia
;
Ferrara, Eva;De Grazia, Alessandra;Cozzi, Denis A
2021

Abstract

A 31-year-old man was referred to an adult urologist for a renal polar mass that measured 7.2 cm in maximum diameter. Robotic assisted complete tumor excision for suspicious renal cell carcinoma was carried out, preserving the rest of the left kidney. Histopathology showed a Wilms tumor (WT) with positive margins. No postoperative therapy was made, and the patient shortly presented an abdominal recurrence. The patient was referred to our pediatric oncology unit; he received preoperative chemotherapy, followed by surgery (completion nephrectomy and removal of neoplastic deposits in the omentum and parietal peritoneum), postoperative chemotherapy, and abdomen radiotherapy. He is well at the 5-year follow-up. Peritoneal dissemination after laparoscopic nephron-sparing surgery (NSS) in a child with a 10-cm WT was previously reported. We suggest open NSS for large WT may be safer than laparoscopic or robotic NSS because carbon dioxide pneumoperitoneum and traumatic handling of tumor may predispose to tumor cell migration. An abdominal WT relapse in adults can be salvaged by multimodal therapy recommended by current pediatric WT guidelines.
2021
adult; recurrence; renal cell carcinoma; Wilms tumor
01 Pubblicazione su rivista::01i Case report
Abdominal recurrence after robotic nephron-sparing surgery for Wilms tumor in an adult patient / Schiavetti, Amalia; Ferrara, Eva; De Grazia, Alessandra; Cozzi, Denis A. - In: UROLOGIA INTERNATIONALIS. - ISSN 1423-0399. - (2021), pp. 1-4. [10.1159/000514595]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1531230
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