Abstract: Background: We present the case of a 55-year-old woman, admitted to the Infectious Disease Department of Policlinico Umberto I, Rome, in mid-March 2020, with suspicion of COVID-19 infection. Objective: The rRT-PCR was negative, and the following CT scan, performed to exclude false-negative results and help diagnosis, was inconclusive. Methods: It was decided to submit the patient to a 99mTc-HMPAO-labelled leukocyte scan. Results: This exam led to the diagnosis of infective endocarditis. Conclusion: In the present pandemic scenario, 99mTc-HMPAO-labelled leukocyte scan represents a reliable imaging technique for differential diagnosis with COVID-19 in patients with confusing clinical signs, possible false-negative rRT-PCR results, and inconclusive CT scan.
COVID-19: how nuclear medicine can provide a differential diagnosis in a very dubious case / De Feo, Maria Silvia; Frantellizzi, Viviana; De Vincentis, Giuseppe. - In: CORONAVIRUSES. - ISSN 2666-7967. - 2:7(2021). [10.2174/2666796701999201209142919]
COVID-19: how nuclear medicine can provide a differential diagnosis in a very dubious case
De Feo, Maria SilviaPrimo
;Frantellizzi, Viviana
Secondo
;De Vincentis, GiuseppeUltimo
2021
Abstract
Abstract: Background: We present the case of a 55-year-old woman, admitted to the Infectious Disease Department of Policlinico Umberto I, Rome, in mid-March 2020, with suspicion of COVID-19 infection. Objective: The rRT-PCR was negative, and the following CT scan, performed to exclude false-negative results and help diagnosis, was inconclusive. Methods: It was decided to submit the patient to a 99mTc-HMPAO-labelled leukocyte scan. Results: This exam led to the diagnosis of infective endocarditis. Conclusion: In the present pandemic scenario, 99mTc-HMPAO-labelled leukocyte scan represents a reliable imaging technique for differential diagnosis with COVID-19 in patients with confusing clinical signs, possible false-negative rRT-PCR results, and inconclusive CT scan.File | Dimensione | Formato | |
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De Feo_COVID-19: How_2020.pdf
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