In the last few years TAM receptors, which are a unique family of receptor tyrosine kinase (RTK), have acquired increasing importance. The aim of our study was to evaluate Mer and Axl TAM receptors expression in malignant melanoma (MM) samples, in order to find clinicopathological features that could explain the different biological behavior of MM. Mer an Axl Tam receptors are a further important pathway that, in the future, could be more studied for the pathogenesis of MM, in order to expand the spectrum of relative target treatments.
Immunohistochemical evaluation and clinicopathological correlation of Mer and Axl tyrosine kinase Tam receptors in cutaneous melanoma / Pontara, Andrea; Paolino, Giovanni; Gregorc, Vanesa; Raffaele Mercuri, Santo; Bulotta, Alessandra; Bearzi, Pietro; Doglioni, Claudio; Rizzo, Nathalie. - (2019). (Intervento presentato al convegno 28th European Academy of Dermatology and Venereology, Congress, Vienna, Austria tenutosi a Madrid, Spain).
Immunohistochemical evaluation and clinicopathological correlation of Mer and Axl tyrosine kinase Tam receptors in cutaneous melanoma
Giovanni Paolino
;
2019
Abstract
In the last few years TAM receptors, which are a unique family of receptor tyrosine kinase (RTK), have acquired increasing importance. The aim of our study was to evaluate Mer and Axl TAM receptors expression in malignant melanoma (MM) samples, in order to find clinicopathological features that could explain the different biological behavior of MM. Mer an Axl Tam receptors are a further important pathway that, in the future, could be more studied for the pathogenesis of MM, in order to expand the spectrum of relative target treatments.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
