We describe serial MR-spectroscopy studies in a patient with systemic lupus erythematosus and headache. We used MR-spectroscopy to monitor disease activity during periods with and without headache. MR-spectroscopy investigates metabolic alterations and was used to explore the pathophysiological mechanism involved in the complications of systemic lupus erythematosus. Our patient underwent serial conventional MRI and MR-spectroscopy at times of controlled and uncontrolled headache, with or without visual aura. MR-spectroscopy showed an increase in the choline/creatine ratio in thalamus and posterior white matter only during periods of uncontrolled headache with visual aura. Conventional MRI scans were normal at all times. MR-spectroscopy should be used in the diagnosis and follow-up of headache in patients with systemic lupus erythematosus.
H-magnetic resonance spectroscopy. diagnostic tool in recurrent headache in systemic lupus erythematosus. a case report / Tinelli, Emanuele; Pontecorvo, Simona; Morreale, Manuela; Caramia, Francesca; Francia, Ada. - In: RADIOLOGY CASE REPORTS. - ISSN 1930-0433. - 14:2(2018), pp. 175-178. [10.1016/j.radcr.2018.10.020]
H-magnetic resonance spectroscopy. diagnostic tool in recurrent headache in systemic lupus erythematosus. a case report
Tinelli, Emanuele
Primo
Writing – Original Draft Preparation
;Pontecorvo, SimonaSecondo
Data Curation
;Morreale, ManuelaData Curation
;Caramia, FrancescaPenultimo
Writing – Review & Editing
;Francia, AdaUltimo
Writing – Review & Editing
2018
Abstract
We describe serial MR-spectroscopy studies in a patient with systemic lupus erythematosus and headache. We used MR-spectroscopy to monitor disease activity during periods with and without headache. MR-spectroscopy investigates metabolic alterations and was used to explore the pathophysiological mechanism involved in the complications of systemic lupus erythematosus. Our patient underwent serial conventional MRI and MR-spectroscopy at times of controlled and uncontrolled headache, with or without visual aura. MR-spectroscopy showed an increase in the choline/creatine ratio in thalamus and posterior white matter only during periods of uncontrolled headache with visual aura. Conventional MRI scans were normal at all times. MR-spectroscopy should be used in the diagnosis and follow-up of headache in patients with systemic lupus erythematosus.File | Dimensione | Formato | |
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