Granulomatous slack skin (GSS) is a rare disorder which is considered a slowly evolving T-cell lymphoma associated with granulomatous inflammation that mediates clastolysis. A combined cytogenetic, molecular, and cellular analysis was conducted on a clinically and histologically defined case of GSS. Cell cultures obtained from the skin biopsy showed trisomy of chromosome 8, and the DNA sample extracted from the skin biopsy showed a T-cell receptor beta-chain rearrangement.

Granulomatous slack skin: cytogenetic and molecular analyses / Grammatico, Paola; Balus, L; Scarpa, Susanna; Varesco, L; Di Rosa, C; Grammatico, B; Del Porto, Giuseppe. - In: CANCER GENETICS AND CYTOGENETICS. - ISSN 0165-4608. - STAMPA. - 72(1994), pp. 96-100. [10.1016/0165-4608(94)90122-8]

Granulomatous slack skin: cytogenetic and molecular analyses.

GRAMMATICO, Paola;SCARPA, Susanna;DEL PORTO, Giuseppe
1994

Abstract

Granulomatous slack skin (GSS) is a rare disorder which is considered a slowly evolving T-cell lymphoma associated with granulomatous inflammation that mediates clastolysis. A combined cytogenetic, molecular, and cellular analysis was conducted on a clinically and histologically defined case of GSS. Cell cultures obtained from the skin biopsy showed trisomy of chromosome 8, and the DNA sample extracted from the skin biopsy showed a T-cell receptor beta-chain rearrangement.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11573/117816
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