Introduction: Chronic pharyngitis is one of the most frequent diseases of the upper aerodigestive pathways. Gastro-esophageal reflux plays an important role in the g this disease. In fact, the excessive exposure of the pharynx to the gastric contents leads to a chronic irritation of the upper airways. On the basis of the foregoing, the study of the present work aims to document the effect of pastilles composed of xanthan gum, sodium hyaluronate, mannitol, sodium hydrogen carbonate, sorbitol, citric acid, aspartame, vitamin C, aroma, zinc citrate dihydrate. variation of salivary pH, of the symptomatology and of the objective picture in subjects affected by secondary interest in acidity of the oral cavity. Materials and methods: 50 subjects were recruited. They were enrolled by the affiliated users to three ENT centers and supported by a gastroenterologist (Naples), 50 (25 males and 25 females) with average age of 37aa, Min 6 aa, Max 65 aa patients affected by secondary to acidity of the oral cavity. For each patient an objective examination was performed and then the salivary pH changes were evaluated, using indicator maps, and furthermore, the Reflux Symptoms Index (RSI) and Reflux Finding Scores (RFS) were administered before, during and after therapy to monitor the subjectivity of the symptomatology and the laryngeal objective picture. Results: The survey performed allowed to establish a clear improvement in all phases of the study, both as regards the effects on pH, both on the side of the symptomatology and on the laryngeal objective. Discussion: The motivation for improving the clinical condition of the subjects is due to the therapeutic properties of the substances used. In particular: the hyaluronic acid has a regenerating power of the mucosa; carbomer and Xanthana Gum have a viscoelastic behavior and contribute to the potency of ac. High molecular weight hyaluronic acid through the formation of a hydrocomplex of high tolerability mucoadhesive polymers. Conclusions: Undoubtedly it is a product capable of restoring the physiological conditions of the oral cavity and the very first airways and their use not only acts as a restoration of the physiological conditions of the oral cavity, but also as a preventive action for the appearance of local and systemic diseases.

Adjuvant therapy with tablets containing sodium jaluronate, carbomer and xantam gum for gerd pharyngitis / Armone Caruso, A; Pennino, A; Del Prete, S; Marasco, D; Miglietta, A; Salzano, J; Cavaliere, C; Masieri, S; Telesca, D A; Sivero, L. - In: INTERNATIONAL JOURNAL OF CURRENT ADVANCED RESEARCH. - ISSN 2319-6505. - 7:7(J)(2018), pp. 14554-14557. [10.24327/ijcar.2018.14557.2642]

Adjuvant therapy with tablets containing sodium jaluronate, carbomer and xantam gum for gerd pharyngitis

Cavaliere C;Masieri S;
2018

Abstract

Introduction: Chronic pharyngitis is one of the most frequent diseases of the upper aerodigestive pathways. Gastro-esophageal reflux plays an important role in the g this disease. In fact, the excessive exposure of the pharynx to the gastric contents leads to a chronic irritation of the upper airways. On the basis of the foregoing, the study of the present work aims to document the effect of pastilles composed of xanthan gum, sodium hyaluronate, mannitol, sodium hydrogen carbonate, sorbitol, citric acid, aspartame, vitamin C, aroma, zinc citrate dihydrate. variation of salivary pH, of the symptomatology and of the objective picture in subjects affected by secondary interest in acidity of the oral cavity. Materials and methods: 50 subjects were recruited. They were enrolled by the affiliated users to three ENT centers and supported by a gastroenterologist (Naples), 50 (25 males and 25 females) with average age of 37aa, Min 6 aa, Max 65 aa patients affected by secondary to acidity of the oral cavity. For each patient an objective examination was performed and then the salivary pH changes were evaluated, using indicator maps, and furthermore, the Reflux Symptoms Index (RSI) and Reflux Finding Scores (RFS) were administered before, during and after therapy to monitor the subjectivity of the symptomatology and the laryngeal objective picture. Results: The survey performed allowed to establish a clear improvement in all phases of the study, both as regards the effects on pH, both on the side of the symptomatology and on the laryngeal objective. Discussion: The motivation for improving the clinical condition of the subjects is due to the therapeutic properties of the substances used. In particular: the hyaluronic acid has a regenerating power of the mucosa; carbomer and Xanthana Gum have a viscoelastic behavior and contribute to the potency of ac. High molecular weight hyaluronic acid through the formation of a hydrocomplex of high tolerability mucoadhesive polymers. Conclusions: Undoubtedly it is a product capable of restoring the physiological conditions of the oral cavity and the very first airways and their use not only acts as a restoration of the physiological conditions of the oral cavity, but also as a preventive action for the appearance of local and systemic diseases.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1136705
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