The control of the HIV infection is considered in the framework of the optimal control theory within the problem of resource allocation. A control action, changing the intervention strategy on the basis of the updated situations, is proposed. The switching instants are not fixed in advance but are determined along with the final control time. A constructive algorithm to compute iteratively the switching control is outlined. The solutions obtained provide interesting and promising results.
HIV infection control: a constructive algorithm for a state-based switching control / Di Giamberardino, Paolo; Iacoviello, Daniela. - In: INTERNATIONAL JOURNAL OF CONTROL, AUTOMATION, AND SYSTEMS. - ISSN 1598-6446. - STAMPA. - 16:3(2018), pp. 1469-1473. [10.1007/s12555-017-0211-2]
HIV infection control: a constructive algorithm for a state-based switching control
Di Giamberardino, Paolo
;Iacoviello, Daniela
2018
Abstract
The control of the HIV infection is considered in the framework of the optimal control theory within the problem of resource allocation. A control action, changing the intervention strategy on the basis of the updated situations, is proposed. The switching instants are not fixed in advance but are determined along with the final control time. A constructive algorithm to compute iteratively the switching control is outlined. The solutions obtained provide interesting and promising results.File | Dimensione | Formato | |
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