In the present study the authors have evaluated at tissue level the gene expression of IL-12, IL-2 and IL-4, in order to asses the functional phenotype of Tumour Infiltrating Lymphocytes in head and neck squamous cell carcinomas. The distribution of lymphocytes present within the neoplastic tissue of larynx carcinomas indicate that these neoplasms are able to induce predominantly Th1 heper lymphocytes.
IL-12 RELATED CYTOKINE GENE EXPRESSION IN CARCINOMAS OF THE LARYNX. A STUDY AT TISSUE LEVEL / Vitolo, Domenico; Gallo, Andrea; Ciocci, L.; Cicerone, E.; Baroni, Carlo. - In: EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY. - ISSN 0937-4477. - STAMPA. - 5:257(2000), pp. 290-294. [10.1007/s004050050243]
IL-12 RELATED CYTOKINE GENE EXPRESSION IN CARCINOMAS OF THE LARYNX. A STUDY AT TISSUE LEVEL.
VITOLO, Domenico;GALLO, Andrea;BARONI, Carlo
2000
Abstract
In the present study the authors have evaluated at tissue level the gene expression of IL-12, IL-2 and IL-4, in order to asses the functional phenotype of Tumour Infiltrating Lymphocytes in head and neck squamous cell carcinomas. The distribution of lymphocytes present within the neoplastic tissue of larynx carcinomas indicate that these neoplasms are able to induce predominantly Th1 heper lymphocytes.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
