FIORENTINO, FRANCESCO
FIORENTINO, FRANCESCO
DIPARTIMENTO DI SCIENZE BIOCHIMICHE "ALESSANDRO ROSSI FANELLI"
(Heteroarylmethyl)benzoic acids as a new class of bacterial cystathionine γ-lyase inhibitors. Synthesis, biological evaluation, and molecular modeling
2024 Golovina, Anastasia; Proia, Eleonora; Fiorentino, Francesco; Yunin, Maxim; Kasatkina, Maria; Zigangirova, Nailya; Soloveva, Anna; Sysolyatina, Elena; Ermolaeva, Svetlana; Novikov, Roman; Silonov, Sergei; Pushkin, Sergei; Mladenović, Milan; Isakova, Julia; Belik, Albina; Nawrozkij, Maxim; Rotili, Dante; Ragno, Rino; Ivanov, Roman
A C3‐Symmetric Diphenylethylendiamine‐Based Catalyst in the Asymmetric Michael Addition of α,β‐Unsaturated Ketones with 4‐Hydroxycoumarin and 4‐Hydroxyquinolin‐2‐One
2025 Oljira, Shilashi Badasa; De Angelis, Martina; Manetto, Simone; Fiorentino, Francesco; Rotili, Dante; Mosca, Luciana; Di Risola, Daniel; Mattioli, Roberto; Pierini, Marco; Mazzoccanti, Giulia; Ciogli, Alessia
A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection
2024 Maure, Alexandra; Lawarée, Emeline; Fiorentino, Francesco; Pawlik, Alexandre; Gona, Saideep; Giraud-Gatineau, Alexandre; Eldridge, Matthew J. G.; Danckaert, Anne; Hardy, David; Frigui, Wafa; Keck, Camille; Gutierrez, Claude; Neyrolles, Olivier; Aulner, Nathalie; Mai, Antonello; Hamon, Mélanie; Barreiro, Luis B.; Brodin, Priscille; Brosch, Roland; Rotili, Dante; Tailleux, Ludovic
Activation and inhibition of sirtuins: From bench to bedside
2024 Fiorentino, Francesco; Fabbrizi, Emanuele; Mai, Antonello; Rotili, Dante
An amazing 30-year journey around the DABO family. A medicinal chemistry lesson on a versatile class of non-nucleoside HIV-1 reverse transcriptase inhibitors
2025 Fabbrizi, Emanuele; Chernyshov, Vladimir V.; Fiorentino, Francesco; Sbardella, Gianluca; Ragno, Rino; Nawrozkij, Maxim; Ivanov, Roman; Rotili, Dante; Mai, Antonello
Anionic dendritic polyglycerol for protein purification and delipidation
2021 Urner, L. H.; Mohammadifar, E.; Ludwig, K.; Shutin, D.; Fiorentino, F.; Liko, I.; Almeida, F. G.; Kutifa, D.; Haag, R.; Robinson, C. V.
Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives
2021 Fiorentino, Francesco; DE ANGELIS, Marta; Menna, Martina; Rovere, Annarita; Maria Caccuri, Anna; D'Acunzo, Francesca; Palamara, ANNA TERESA; Nencioni, Lucia; Rotili, Dante; Mai, Antonello
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII
2023 Fiorentino, Francesco; Nocentini, Alessio; Rotili, Dante; Supuran, Claudiu T; Mai, Antonello
Assembly and regulation of the chlorhexidine-specific efflux pump AceI
2020 Bolla, J. R.; Howes, A. C.; Fiorentino, F.; Robinson, C. V.
Biochemical functions and clinical characterizations of the sirtuins in diabetes-induced retinal pathologies
2022 Taurone, Samanta; DE PONTE, Chiara; Rotili, Dante; DE SANTIS, Elena; Mai, Antonello; Fiorentino, Francesco; Scarpa, Susanna; Artico, Marco; Micera, Alessandra
Design and synthesis of novel compounds targeting both AURKA and HDAC enzymes.
2024 Ruggieri, G.; Madia, V. N.; Patacchini, E.; Ialongo, D.; Albano, A.; Messore, A.; Saccoliti, F; Arpacioglu, M.; De Leo, A.; Scipione, L.; Rotili, D.; Fiorentino, F.; Paiardini, A.; Di Santo, R.; Costi, R.
Design of Benzyl-triazolopyrimidine-Based NADPH Oxidase Inhibitors Leads to the Discovery of a Potent Dual Covalent NOX2/MAOB Inhibitor
2025 Noce, Beatrice; Marchese, Sara; Massari, Marta; Lambona, Chiara; Reis, Joana; Fiorentino, Francesco; Raucci, Alessia; Fioravanti, Rossella; Castelôa, Mariana; Mormino, Alessandro; Garofalo, Stefano; Limatola, Cristina; Basile, Lorenzo; Gottinger, Andrea; Binda, Claudia; Mattevi, Andrea; Mai, Antonello; Valente, Sergio
Detergents and methods
2022 Urner Leonhard, Hagen; Pagel, Kevin; Haag, Rainer; Shutin, Denis; Agasid, Mark; Fiorentino, Francesco; Carol V., Robinson
Detergents with Scalable Properties Identify Noncanonical Lipopolysaccharide Binding to Bacterial Inner Membrane Proteins
2024 Urner, Leonhard H; Fiorentino, Francesco; Shutin, Denis; Sauer, Joshua B; Agasid, Mark T; El-Baba, Tarick J; Bolla, Jani R; Stansfeld, Phillip J; Robinson, Carol V
DEVELOPING NOVEL COMPOUNDS TARGETING AURKA AND HDAC ENZYMES SIMULTANEOUSLY
2024 Arpacioglu, M.; Madia, V. N.; Patacchini, E.; Ialongo, D.; Albano, A.; Messore, A.; Ruggieri, G.; De Leo, A.; Scipione, L.; Rotili, D.; Fiorentino, F.; Paiardini, A.; Di Santo, R.; Costi, R.
Development of C646‐based proteolysis targeting chimeras degraders of the lysine acetyltransferases CBP and p300
2025 Fiorentino, Francesco; Spriano, Filippo; Tomaselli, Daniela; Risi, Giorgia; Fabbrizi, Emanuele; Pecci, Valeria; Nanni, Simona; Bertoni, Francesco; Rotili, Dante; Mai, Antonello
Dynamics of an LPS translocon induced by substrate and an antimicrobial peptide
2021 Fiorentino, F.; Sauer, J. B.; Qiu, X.; Corey, R. A.; Cassidy, C. K.; Mynors-Wallis, B.; Mehmood, S.; Bolla, J. R.; Stansfeld, P. J.; Robinson, C. V.
Emerging roles of SIRT5 in metabolism, cancer, and SARS-CoV-2 infection
2023 Fabbrizi, Emanuele; Fiorentino, Francesco; Carafa, Vincenzo; Altucci, Lucia; Mai, Antonello; Rotili, Dante
Emerging therapeutic potential of SIRT6 modulators
2021 Fiorentino, F.; Mai, A.; Rotili, D.
First-in-class selective inhibitors of the lysine acetyltransferase KAT8
2023 Fiorentino, Francesco; Sementilli, Sara; Menna, Martina; Turrisi, Federica; Tomassi, Stefano; Pellegrini, FRANCESCA ROMANA; Iuzzolino, Angela; D'Acunzo, Francesca; Feoli, Alessandra; Wapenaar, Hannah; Taraglio, Sophie; Fraschetti, Caterina; Del Bufalo, Donatella; Sbardella, Gianluca; Dekker, Frank J.; Paiardini, Alessandro; Trisciuoglio, Daniela; Mai, Antonello; Rotili, Dante
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| (Heteroarylmethyl)benzoic acids as a new class of bacterial cystathionine γ-lyase inhibitors. Synthesis, biological evaluation, and molecular modeling | 2024 | Golovina, Anastasia; Proia, Eleonora; Fiorentino, Francesco; Yunin, Maxim; Kasatkina, Maria; Zigangirova, Nailya; Soloveva, Anna; Sysolyatina, Elena; Ermolaeva, Svetlana; Novikov, Roman; Silonov, Sergei; Pushkin, Sergei; Mladenović, Milan; Isakova, Julia; Belik, Albina; Nawrozkij, Maxim; Rotili, Dante; Ragno, Rino; Ivanov, Roman | |
| A C3‐Symmetric Diphenylethylendiamine‐Based Catalyst in the Asymmetric Michael Addition of α,β‐Unsaturated Ketones with 4‐Hydroxycoumarin and 4‐Hydroxyquinolin‐2‐One | 2025 | Oljira, Shilashi Badasa; De Angelis, Martina; Manetto, Simone; Fiorentino, Francesco; Rotili, Dante; Mosca, Luciana; Di Risola, Daniel; Mattioli, Roberto; Pierini, Marco; Mazzoccanti, Giulia; Ciogli, Alessia | |
| A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection | 2024 | Maure, Alexandra; Lawarée, Emeline; Fiorentino, Francesco; Pawlik, Alexandre; Gona, Saideep; Giraud-Gatineau, Alexandre; Eldridge, Matthew J. G.; Danckaert, Anne; Hardy, David; Frigui, Wafa; Keck, Camille; Gutierrez, Claude; Neyrolles, Olivier; Aulner, Nathalie; Mai, Antonello; Hamon, Mélanie; Barreiro, Luis B.; Brodin, Priscille; Brosch, Roland; Rotili, Dante; Tailleux, Ludovic | |
| Activation and inhibition of sirtuins: From bench to bedside | 2024 | Fiorentino, Francesco; Fabbrizi, Emanuele; Mai, Antonello; Rotili, Dante | |
| An amazing 30-year journey around the DABO family. A medicinal chemistry lesson on a versatile class of non-nucleoside HIV-1 reverse transcriptase inhibitors | 2025 | Fabbrizi, Emanuele; Chernyshov, Vladimir V.; Fiorentino, Francesco; Sbardella, Gianluca; Ragno, Rino; Nawrozkij, Maxim; Ivanov, Roman; Rotili, Dante; Mai, Antonello | |
| Anionic dendritic polyglycerol for protein purification and delipidation | 2021 | Urner, L. H.; Mohammadifar, E.; Ludwig, K.; Shutin, D.; Fiorentino, F.; Liko, I.; Almeida, F. G.; Kutifa, D.; Haag, R.; Robinson, C. V. | |
| Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives | 2021 | Fiorentino, Francesco; DE ANGELIS, Marta; Menna, Martina; Rovere, Annarita; Maria Caccuri, Anna; D'Acunzo, Francesca; Palamara, ANNA TERESA; Nencioni, Lucia; Rotili, Dante; Mai, Antonello | |
| Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII | 2023 | Fiorentino, Francesco; Nocentini, Alessio; Rotili, Dante; Supuran, Claudiu T; Mai, Antonello | |
| Assembly and regulation of the chlorhexidine-specific efflux pump AceI | 2020 | Bolla, J. R.; Howes, A. C.; Fiorentino, F.; Robinson, C. V. | |
| Biochemical functions and clinical characterizations of the sirtuins in diabetes-induced retinal pathologies | 2022 | Taurone, Samanta; DE PONTE, Chiara; Rotili, Dante; DE SANTIS, Elena; Mai, Antonello; Fiorentino, Francesco; Scarpa, Susanna; Artico, Marco; Micera, Alessandra | |
| Design and synthesis of novel compounds targeting both AURKA and HDAC enzymes. | 2024 | Ruggieri, G.; Madia, V. N.; Patacchini, E.; Ialongo, D.; Albano, A.; Messore, A.; Saccoliti, F; Arpacioglu, M.; De Leo, A.; Scipione, L.; Rotili, D.; Fiorentino, F.; Paiardini, A.; Di Santo, R.; Costi, R. | |
| Design of Benzyl-triazolopyrimidine-Based NADPH Oxidase Inhibitors Leads to the Discovery of a Potent Dual Covalent NOX2/MAOB Inhibitor | 2025 | Noce, Beatrice; Marchese, Sara; Massari, Marta; Lambona, Chiara; Reis, Joana; Fiorentino, Francesco; Raucci, Alessia; Fioravanti, Rossella; Castelôa, Mariana; Mormino, Alessandro; Garofalo, Stefano; Limatola, Cristina; Basile, Lorenzo; Gottinger, Andrea; Binda, Claudia; Mattevi, Andrea; Mai, Antonello; Valente, Sergio | |
| Detergents and methods | 2022 | Urner Leonhard, Hagen; Pagel, Kevin; Haag, Rainer; Shutin, Denis; Agasid, Mark; Fiorentino, Francesco; Carol V., Robinson | |
| Detergents with Scalable Properties Identify Noncanonical Lipopolysaccharide Binding to Bacterial Inner Membrane Proteins | 2024 | Urner, Leonhard H; Fiorentino, Francesco; Shutin, Denis; Sauer, Joshua B; Agasid, Mark T; El-Baba, Tarick J; Bolla, Jani R; Stansfeld, Phillip J; Robinson, Carol V | |
| DEVELOPING NOVEL COMPOUNDS TARGETING AURKA AND HDAC ENZYMES SIMULTANEOUSLY | 2024 | Arpacioglu, M.; Madia, V. N.; Patacchini, E.; Ialongo, D.; Albano, A.; Messore, A.; Ruggieri, G.; De Leo, A.; Scipione, L.; Rotili, D.; Fiorentino, F.; Paiardini, A.; Di Santo, R.; Costi, R. | |
| Development of C646‐based proteolysis targeting chimeras degraders of the lysine acetyltransferases CBP and p300 | 2025 | Fiorentino, Francesco; Spriano, Filippo; Tomaselli, Daniela; Risi, Giorgia; Fabbrizi, Emanuele; Pecci, Valeria; Nanni, Simona; Bertoni, Francesco; Rotili, Dante; Mai, Antonello | |
| Dynamics of an LPS translocon induced by substrate and an antimicrobial peptide | 2021 | Fiorentino, F.; Sauer, J. B.; Qiu, X.; Corey, R. A.; Cassidy, C. K.; Mynors-Wallis, B.; Mehmood, S.; Bolla, J. R.; Stansfeld, P. J.; Robinson, C. V. | |
| Emerging roles of SIRT5 in metabolism, cancer, and SARS-CoV-2 infection | 2023 | Fabbrizi, Emanuele; Fiorentino, Francesco; Carafa, Vincenzo; Altucci, Lucia; Mai, Antonello; Rotili, Dante | |
| Emerging therapeutic potential of SIRT6 modulators | 2021 | Fiorentino, F.; Mai, A.; Rotili, D. | |
| First-in-class selective inhibitors of the lysine acetyltransferase KAT8 | 2023 | Fiorentino, Francesco; Sementilli, Sara; Menna, Martina; Turrisi, Federica; Tomassi, Stefano; Pellegrini, FRANCESCA ROMANA; Iuzzolino, Angela; D'Acunzo, Francesca; Feoli, Alessandra; Wapenaar, Hannah; Taraglio, Sophie; Fraschetti, Caterina; Del Bufalo, Donatella; Sbardella, Gianluca; Dekker, Frank J.; Paiardini, Alessandro; Trisciuoglio, Daniela; Mai, Antonello; Rotili, Dante |