COLOTTI, GIANNI
COLOTTI, GIANNI
DIPARTIMENTO DI SCIENZE BIOCHIMICHE "ALESSANDRO ROSSI FANELLI"
Bcl-2 family inhibitors sensitize human cancer models to therapy
2023 Valentini, Elisabetta; Di Martile, Marta; Brignone, Matteo; Di Caprio, Marica; Manni, Isabella; Chiappa, Michela; Sergio, Ilaria; Chiacchiarini, Martina; Bazzichetto, Chiara; Conciatori, Fabiana; D'Aguanno, Simona; D'Angelo, Carmen; Ragno, Rino; Russillo, Michelangelo; Colotti, Gianni; Marchesi, Francesco; Bellone, Maria Laura; Dal Piaz, Fabrizio; Felli, Maria Pia; Damia, Giovanna; Del Bufalo, Donatella
Bioinformatics analysis of Ras homologue enriched in the striatum, a potential target for Huntington's disease therapy
2019 Carbo, M.; Brandi, V.; Pascarella, G.; Staid, DAVID SASAH; Colotti, G.; Polticelli, F.; Ilari, A.; Morea, V.
Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability
2022 Tramonti, Angela; Ghatge, Mohini S; Babor, Jill T; Musayev, Faik N; di Salvo, Martino Luigi; Barile, Anna; Colotti, Gianni; Giorgi, Alessandra; Paredes, Steven D; Donkor, Akua K; Al Mughram, Mohammed H; de Crécy-Lagard, Valérie; Safo, Martin K; Contestabile, Roberto
Doxorubicin and other anthracyclines in cancers: activity, chemoresistance and its overcoming
2023 Mattioli, R.; Ilari, A.; Colotti, B.; Mosca, L.; Fazi, F.; Colotti, G.
ERp57 chaperon protein protects neuronal cells from Aβ-induced toxicity
2022 Di Risola, Daniel; Ricci, Daniela; Marrocco, Ilaria; Giamogante, Flavia; Grieco, Maddalena; Francioso, Antonio; Vasco-Vidal, Aldrin; Mancini, Patrizia; Colotti, Gianni; Mosca, Luciana; Altieri, Fabio
Exogenous peptides are able to penetrate human cell and mitochondrial membranes, stabilize mitochondrial tRNA structures, and rescue severe mitochondrial defects
2020 Perli, Elena; Pisano, Annalinda; Pignataro, Maria Gemma; Campese, Antonio Francesco; Pelullo, Maria; Genovese, Ilaria; de Turris, Valeria; Ghelli, Anna Maria; Cerbelli, Bruna; Giordano, Carla; Colotti, Gianni; Morea, Veronica; D'Amati, Giulia
Glucose transportation in the brain and its impairment in Huntington disease: one more shade of the energetic metabolism failure?
2017 Morea, Veronica; Bidollari, Eris; Colotti, Gianni; Fiorillo, Annarita; Rosati, Jessica Diana; De Filippis, Lidia; Squitieri, Ferdinando; Ilari, Andrea
Huntingtin ubiquitination mechanisms and novel possible therapies to decrease the toxic effects of mutated huntingtin
2021 Fiorillo, A.; Morea, V.; Colotti, G.; Ilari, A.
Identification of chalcone-based antileishmanial agents targeting trypanothione reductase
2018 Ortalli, M; Ilari, Andrea; Colotti, G; De Ionna, I; Battista, Theo; Bisi, A; Gobbi, S; Rampa, A; Di Martino RMC, ; Gentilomi, Ga; Varani, S; Belluti, F.
Identification of small molecule inhibitors of the aurora-A/TPX2 complex
2017 Asteriti, ITALIA ANNA; Daidone, F; Colotti, G; Rinaldo, Serena; Lavia, P; Guarguaglini, Giulia; Paiardini, Alessandro
Inhibition of Leishmania infantum Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site
2023 Madia, Valentina Noemi; Ialongo, Davide; Patacchini, Elisa; Exertier, Cécile; Antonelli, Lorenzo; Colotti, Gianni; Messore, Antonella; Tudino, Valeria; Saccoliti, Francesco; Scipione, Luigi; Ilari, Andrea; Costi, Roberta; Di Santo, Roberto Di
Inhibitory effect of silver nanoparticles on trypanothione reductase activity and leishmania infantum proliferation
2010 Baiocco, P.; Ilari, A.; Ceci, P.; Orsini, S.; Gramiccia, M.; Di Muccio, T.; Colotti, G.
Innovative approach for a classic target: fragment screening on trypanothione reductase reveals new opportunities for drug design
2022 Fiorillo, A; Colotti, G; Exertier, C; Liuzzi, A; Seghetti, F; Salerno, A; Caciolla, J; Ilari, Andrea
Investigation of the entry pathway and molecular nature of σ1 receptor ligands
2023 Pascarella, Gianmarco; Antonelli, Lorenzo; Narzi, Daniele; Battista, Theo; Fiorillo, Annarita; Colotti, Gianni; Guidoni, Leonardo; Morea, Veronica; Ilari, Andrea
Known drugs identified by structure-based virtual screening are able to bind sigma-1 receptor and increase growth of huntington disease patient-derived cells
2021 Battista, T.; Pascarella, G.; Staid, D. S.; Colotti, G.; Rosati, J.; Fiorillo, A.; Casamassa, A.; Vescovi, A. L.; Giabbai, B.; Semrau, M. S.; Fanelli, S.; Storici, P.; Squitieri, F.; Morea, V.; Ilari, A.
Leishmania infantum trypanothione reductase is a promiscuous enzyme carrying an nadph:o2 oxidoreductase activity shared by glutathione reductase
2015 Angiulli, Gabriella; Lantella, A.; Forte, Elena; Angelucci, F.; Colotti, G.; Ilari, Andrea; Malatesta, Francesco
Molecular bases of Sorcin-dependent resistance to chemotherapeutic agents
2018 Genovese, Ilaria; Ilari, Andrea; Battista, Theo; Chiarini, Valerio; Fazi, Francesco; Fiorillo, Annarita; Colotti, Gianni
Molecular basis of antimony treatment in leishmaniasis
2009 Baiocco, P.; Colotti, G.; Franceschini, S.; Ilari, A.
Nose-to-brain selective drug delivery to glioma via ferritin-based nanovectors reduces tumor growth and improves survival rate
2024 Marrocco, Francesco; Falvo, Elisabetta; Mosca, Luciana; Tisci, Giada; Arcovito, Alessandro; Reccagni, Alice; Limatola, Cristina; Bernardini, Roberta; Ceci, Pierpaolo; D'Alessandro, Giuseppina; Colotti, Gianni
Optimization of potent and specific trypanothione reductase inhibitors. A structure-based drug discovery approach
2022 Battista, T.; Federico, S.; Brogi, S.; Pozzetti, L.; Khan, T.; Butini, S.; Ramunno, A.; Fiorentino, E.; Orsini, S.; Di Muccio, T.; Fiorillo, A.; Exertier, C.; Di Risola, D.; Colotti, G.; Gemma, S.; Ilari, A.; Campiani, G.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Bcl-2 family inhibitors sensitize human cancer models to therapy | 2023 | Valentini, Elisabetta; Di Martile, Marta; Brignone, Matteo; Di Caprio, Marica; Manni, Isabella; Chiappa, Michela; Sergio, Ilaria; Chiacchiarini, Martina; Bazzichetto, Chiara; Conciatori, Fabiana; D'Aguanno, Simona; D'Angelo, Carmen; Ragno, Rino; Russillo, Michelangelo; Colotti, Gianni; Marchesi, Francesco; Bellone, Maria Laura; Dal Piaz, Fabrizio; Felli, Maria Pia; Damia, Giovanna; Del Bufalo, Donatella | |
| Bioinformatics analysis of Ras homologue enriched in the striatum, a potential target for Huntington's disease therapy | 2019 | Carbo, M.; Brandi, V.; Pascarella, G.; Staid, DAVID SASAH; Colotti, G.; Polticelli, F.; Ilari, A.; Morea, V. | |
| Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability | 2022 | Tramonti, Angela; Ghatge, Mohini S; Babor, Jill T; Musayev, Faik N; di Salvo, Martino Luigi; Barile, Anna; Colotti, Gianni; Giorgi, Alessandra; Paredes, Steven D; Donkor, Akua K; Al Mughram, Mohammed H; de Crécy-Lagard, Valérie; Safo, Martin K; Contestabile, Roberto | |
| Doxorubicin and other anthracyclines in cancers: activity, chemoresistance and its overcoming | 2023 | Mattioli, R.; Ilari, A.; Colotti, B.; Mosca, L.; Fazi, F.; Colotti, G. | |
| ERp57 chaperon protein protects neuronal cells from Aβ-induced toxicity | 2022 | Di Risola, Daniel; Ricci, Daniela; Marrocco, Ilaria; Giamogante, Flavia; Grieco, Maddalena; Francioso, Antonio; Vasco-Vidal, Aldrin; Mancini, Patrizia; Colotti, Gianni; Mosca, Luciana; Altieri, Fabio | |
| Exogenous peptides are able to penetrate human cell and mitochondrial membranes, stabilize mitochondrial tRNA structures, and rescue severe mitochondrial defects | 2020 | Perli, Elena; Pisano, Annalinda; Pignataro, Maria Gemma; Campese, Antonio Francesco; Pelullo, Maria; Genovese, Ilaria; de Turris, Valeria; Ghelli, Anna Maria; Cerbelli, Bruna; Giordano, Carla; Colotti, Gianni; Morea, Veronica; D'Amati, Giulia | |
| Glucose transportation in the brain and its impairment in Huntington disease: one more shade of the energetic metabolism failure? | 2017 | Morea, Veronica; Bidollari, Eris; Colotti, Gianni; Fiorillo, Annarita; Rosati, Jessica Diana; De Filippis, Lidia; Squitieri, Ferdinando; Ilari, Andrea | |
| Huntingtin ubiquitination mechanisms and novel possible therapies to decrease the toxic effects of mutated huntingtin | 2021 | Fiorillo, A.; Morea, V.; Colotti, G.; Ilari, A. | |
| Identification of chalcone-based antileishmanial agents targeting trypanothione reductase | 2018 | Ortalli, M; Ilari, Andrea; Colotti, G; De Ionna, I; Battista, Theo; Bisi, A; Gobbi, S; Rampa, A; Di Martino RMC, ; Gentilomi, Ga; Varani, S; Belluti, F. | |
| Identification of small molecule inhibitors of the aurora-A/TPX2 complex | 2017 | Asteriti, ITALIA ANNA; Daidone, F; Colotti, G; Rinaldo, Serena; Lavia, P; Guarguaglini, Giulia; Paiardini, Alessandro | |
| Inhibition of Leishmania infantum Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site | 2023 | Madia, Valentina Noemi; Ialongo, Davide; Patacchini, Elisa; Exertier, Cécile; Antonelli, Lorenzo; Colotti, Gianni; Messore, Antonella; Tudino, Valeria; Saccoliti, Francesco; Scipione, Luigi; Ilari, Andrea; Costi, Roberta; Di Santo, Roberto Di | |
| Inhibitory effect of silver nanoparticles on trypanothione reductase activity and leishmania infantum proliferation | 2010 | Baiocco, P.; Ilari, A.; Ceci, P.; Orsini, S.; Gramiccia, M.; Di Muccio, T.; Colotti, G. | |
| Innovative approach for a classic target: fragment screening on trypanothione reductase reveals new opportunities for drug design | 2022 | Fiorillo, A; Colotti, G; Exertier, C; Liuzzi, A; Seghetti, F; Salerno, A; Caciolla, J; Ilari, Andrea | |
| Investigation of the entry pathway and molecular nature of σ1 receptor ligands | 2023 | Pascarella, Gianmarco; Antonelli, Lorenzo; Narzi, Daniele; Battista, Theo; Fiorillo, Annarita; Colotti, Gianni; Guidoni, Leonardo; Morea, Veronica; Ilari, Andrea | |
| Known drugs identified by structure-based virtual screening are able to bind sigma-1 receptor and increase growth of huntington disease patient-derived cells | 2021 | Battista, T.; Pascarella, G.; Staid, D. S.; Colotti, G.; Rosati, J.; Fiorillo, A.; Casamassa, A.; Vescovi, A. L.; Giabbai, B.; Semrau, M. S.; Fanelli, S.; Storici, P.; Squitieri, F.; Morea, V.; Ilari, A. | |
| Leishmania infantum trypanothione reductase is a promiscuous enzyme carrying an nadph:o2 oxidoreductase activity shared by glutathione reductase | 2015 | Angiulli, Gabriella; Lantella, A.; Forte, Elena; Angelucci, F.; Colotti, G.; Ilari, Andrea; Malatesta, Francesco | |
| Molecular bases of Sorcin-dependent resistance to chemotherapeutic agents | 2018 | Genovese, Ilaria; Ilari, Andrea; Battista, Theo; Chiarini, Valerio; Fazi, Francesco; Fiorillo, Annarita; Colotti, Gianni | |
| Molecular basis of antimony treatment in leishmaniasis | 2009 | Baiocco, P.; Colotti, G.; Franceschini, S.; Ilari, A. | |
| Nose-to-brain selective drug delivery to glioma via ferritin-based nanovectors reduces tumor growth and improves survival rate | 2024 | Marrocco, Francesco; Falvo, Elisabetta; Mosca, Luciana; Tisci, Giada; Arcovito, Alessandro; Reccagni, Alice; Limatola, Cristina; Bernardini, Roberta; Ceci, Pierpaolo; D'Alessandro, Giuseppina; Colotti, Gianni | |
| Optimization of potent and specific trypanothione reductase inhibitors. A structure-based drug discovery approach | 2022 | Battista, T.; Federico, S.; Brogi, S.; Pozzetti, L.; Khan, T.; Butini, S.; Ramunno, A.; Fiorentino, E.; Orsini, S.; Di Muccio, T.; Fiorillo, A.; Exertier, C.; Di Risola, D.; Colotti, G.; Gemma, S.; Ilari, A.; Campiani, G. |