RUFFOLO, GABRIELE
RUFFOLO, GABRIELE
DIPARTIMENTO DI FISIOLOGIA E FARMACOLOGIA "VITTORIO ERSPAMER"
A novel action of lacosamide on GABAAcurrents sets the ground for a synergic interaction with levetiracetam in treatment of epilepsy
2018 Ruffolo, Gabriele; Di Bonaventura, Carlo; Cifelli, Pierangelo; Roseti, Cristina; Fattouch, Jinane; Morano, Alessandra; Limatola, Cristina; Aronica, Eleonora; Palma, Eleonora; Giallonardo, Anna Teresa
A novel GABAergic dysfunction in human Dravet syndrome
2018 Ruffolo, Gabriele; Cifelli, Pierangelo; Roseti, Cristina; Thom, Maria; van Vliet, Erwin A.; Limatola, Cristina; Aronica, Eleonora; Palma, Eleonora
A systems-level analysis highlights microglial activation as a modifying factor in common epilepsies
2022 Altmann, Andre; Ryten, Mina; Di Nunzio, Martina; Ravizza, Teresa; Tolomeo, Daniele; Reynolds, Regina H; Somani, Alyma; Bacigaluppi, Marco; Iori, Valentina; Micotti, Edoardo; Di Sapia, Rossella; Cerovic, Milica; Palma, Eleonora; Ruffolo, Gabriele; Botía, Juan A; Absil, Julie; Alhusaini, Saud; Alvim, Marina K M; Auvinen, Pia; Bargallo, Nuria; Bartolini, Emanuele; Bender, Benjamin; Bergo, Felipe P G; Bernardes, Tauana; Bernasconi, Andrea; Bernasconi, Neda; Bernhardt, Boris C; Blackmon, Karen; Braga, Barbara; Caligiuri, Maria Eugenia; Calvo, Anna; Carlson, Chad; Carr, Sarah J; Cavalleri, Gianpiero L; Cendes, Fernando; Chen, Jian; Chen, Shuai; Cherubini, Andrea; Concha, Luis; David, Philippe; Delanty, Norman; Depondt, Chantal; Devinsky, Orrin; Doherty, Colin P; Domin, Martin; Focke, Niels K; Foley, Sonya; Franca, Wendy; Gambardella, Antonio; Guerrini, Renzo; Hamandi, Khalid; Hibar, Derrek P; Isaev, Dmitry; Jackson, Graeme D; Jahanshad, Neda; Kalviainen, Reetta; Keller, Simon S; Kochunov, Peter; Kotikalapudi, Raviteja; Kowalczyk, Magdalena A; Kuzniecky, Ruben; Kwan, Patrick; Labate, Angelo; Langner, Soenke; Lenge, Matteo; Liu, Min; Martin, Pascal; Mascalchi, Mario; Meletti, Stefano; Morita-Sherman, Marcia E; O'Brien, Terence J; Pariente, Jose C; Richardson, Mark P; Rodriguez-Cruces, Raul; Rummel, Christian; Saavalainen, Taavi; Semmelroch, Mira K; Severino, Mariasavina; Striano, Pasquale; Thesen, Thomas; Thomas, Rhys H; Tondelli, Manuela; Tortora, Domenico; Vaudano, Anna Elisabetta; Vivash, Lucy; von Podewils, Felix; Wagner, Jan; Weber, Bernd; Wiest, Roland; Yasuda, Clarissa L; Zhang, Guohao; Zhang, Junsong; Leu, Costin; Avbersek, Andreja; Thom, Maria; Whelan, Christopher D; Thompson, Paul; Mcdonald, Carrie R; Vezzani, Annamaria; Sisodiya, Sanjay M
Acetylcholine receptors from human muscle as pharmacological targets for ALS therapy
2016 Palma, E.; Reyes-Ruiz, J. M.; Lopergolo, D.; Roseti, C.; Bertollini, C.; Ruffolo, G.; Cifelli, P.; Onesti, E.; Limatola, C.; Miledi, R.; Inghilleri, M.
Acetylcholine receptors from human muscle as pharmacological targets for ALS therapy
2016 Palma, Eleonora; Reyes Ruiz, Jorge Mauricio; Lopergolo, Diego; Roseti, Cristina; Bertollini, Cristina; Ruffolo, Gabriele; Cifelli, Pierangelo; Onesti, Emanuela; Limatola, Cristina; Miledi, Ricardo; Inghilleri, Maurizio
An unbalanced synaptic transmission. Cause or consequence of the amyloid oligomers neurotoxicity?
2021 Sciaccaluga, M.; Megaro, A.; Bellomo, G.; Ruffolo, G.; Romoli, M.; Palma, E.; Costa, C.
Cannabis in Epilepsy: from clinical practice to basic research focusing on the possible role of cannabidivarin
2016 Morano, Alessandra; Cifelli, Pierangelo; Antonilli, Letizia; Fattouch, Jinane; Ruffolo, Gabriele; Aronica, E; Limatola, Cristina; DI BONAVENTURA, Carlo; Giallonardo, Anna Teresa; Nencini, Paolo; Roseti, Cristina; Palma, Eleonora
Classical and Unexpected Effects of Ultra-Micronized {PEA} in Neuromuscular Function
2022 Cifelli, Pierangelo; Ruffolo, Gabriele; Ceccanti, Marco; Cambieri, Chiara; Libonati, Laura; Palma, Eleonora; Inghilleri, Maurizio
Dissecting the molecular determinants of GABAA receptors current rundown, a hallmark of refractory human epilepsy
2021 Cifelli, Pierangelo; Di Angelantonio, Silvia; Alfano, Veronica; Morano, Alessandra; De Felice, Eleonora; Aronica, Eleonora; Ruffolo, Gabriele; Palma, Eleonora
Editorial: epilepsy and neurodevelopmental diseases
2020 Ruffolo, G.; Van Vliet, E. A.; Aronica, E.; Palma, E.
Effects of 3,4-diaminopyridine on myasthenia gravis: Preliminary results of an open-label study
2022 Ceccanti, Marco; Libonati, Laura; Ruffolo, Gabriele; Cifelli, Pierangelo; Moret, Federica; Frasca, Vittorio; Palma, Eleonora; Inghilleri, Maurizio; Cambieri, Chiara
Erythropoietin increases GABA a currents in human cortex from TLE patients
2019 Roseti, Cristina; Cifelli, Pierangelo; Ruffolo, Gabriele; Barbieri, Elena; Guescini, Michele; Esposito, Vincenzo; Di Gennaro, Giancarlo; Limatola, Cristina; Giovannelli, Aldo; Aronica, Eleonora; Palma, Eleonora
Functional aspects of early brain development are preserved in tuberous sclerosis complex (TSC) epileptogenic lesions
2016 Ruffolo, Gabriele; Iyer, Anand; Cifelli, Pierangelo; Roseti, Cristina; Mühlebner, Angelika; van Scheppingen, Jackelien; Scholl, Theresa; Hainfellner, Johannes A.; Feucht, Martha; Krsek, Pavel; Zamecnik, Josef; Jansen, Floor E.; Spliet, Wim G. M.; Limatola, Cristina; Aronica, Eleonora; Palma, Eleonora
Functional Gastrointestinal Disorders in Patients With Epilepsy: Reciprocal Influence and Impact on Seizure Occurrence
2021 Avorio, F.; Cerulli Irelli, E.; Morano, A.; Fanella, M.; Orlando, B.; Albini, M.; Basili, L. M.; Ruffolo, G.; Fattouch, J.; Manfredi, M.; Russo, E.; Striano, P.; Carabotti, M.; Giallonardo, A. T.; Severi, C.; Di Bonaventura, C.
GABAA currents are decreased by IL-1β in epileptogenic tissue of patients with temporal lobe epilepsy: implications for ictogenesis
2015 Roseti, Cristina; van Vliet, Erwin A; Cifelli, Pierangelo; Ruffolo, Gabriele; Baayen, Johannes C; DI CASTRO, MARIA AMALIA; Bertollini, Cristina; Limatola, Cristina; Aronica, Eleonora; Vezzani, Annamaria; Palma, Eleonora
GABAA receptor function is enhanced by Interleukin-10 in human epileptogenic gangliogliomas and its effect is counteracted by Interleukin-1β
2022 Ruffolo, Gabriele; Alfano, Veronica; Romagnolo, Alessia; Zimmer, Till; Mills, James D; Cifelli, Pierangelo; Gaeta, Alessandro; Morano, Alessandra; Anink, Jasper; Mühlebner, Angelika; Vezzani, Annamaria; Aronica, Eleonora; Palma, Eleonora
GABAergic neurotransmission in human tissues is modulated by cannabidiol
2022 Ruffolo, Gabriele; Gaeta, Alessandro; Cannata, Beatrice; Pinzaglia, Camilla; Aronica, Eleonora; Morano, Alessandra; Cifelli, Pierangelo; Palma, Eleonora
Human iPSC Modeling of Genetic Febrile Seizure Reveals Aberrant Molecular and Physiological Features Underlying an Impaired Neuronal Activity
2022 Scalise, Stefania; Zannino, Clara; Lucchino, Valeria; Lo Conte, Michela; Scaramuzzino, Luana; Cifelli, Pierangelo; D'Andrea, Tiziano; Martinello, Katiuscia; Fucile, Sergio; Palma, Eleonora; Gambardella, Antonio; Ruffolo, Gabriele; Cuda, Giovanni; Immacolata Parrotta, Elvira
Immune-mediated myogenesis and acetylcholine receptor clustering promote a slow disease progression in ALS mouse models
2023 Margotta, Cassandra; Fabbrizio, Paola; Ceccanti, Marco; Cambieri, Chiara; Ruffolo, Gabriele; D'Agostino, Jessica; Trolese, Maria Chiara; Cifelli, Pierangelo; Alfano, Veronica; Laurini, Christian; Scaricamazza, Silvia; Ferri, Alberto; Sorarù, Gianni; Palma, Eleonora; Inghilleri, Maurizio; Bendotti, Caterina; Nardo, Giovanni
Impaired GABAergic regulation and developmental immaturity in interneurons derived from the medial ganglionic eminence in the tuberous sclerosis complex
2024 Scheper, M.; Sorensen, F. N. F.; Ruffolo, G.; Gaeta, A.; Lissner, L. J.; Anink, J. J.; Korshunova, I.; Jansen, F. E.; Riney, K.; van Hecke, W.; Muhlebner, A.; Khodosevich, K.; Schubert, D.; Palma, E.; Mills, J. D.; Aronica, E.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A novel action of lacosamide on GABAAcurrents sets the ground for a synergic interaction with levetiracetam in treatment of epilepsy | 2018 | Ruffolo, Gabriele; Di Bonaventura, Carlo; Cifelli, Pierangelo; Roseti, Cristina; Fattouch, Jinane; Morano, Alessandra; Limatola, Cristina; Aronica, Eleonora; Palma, Eleonora; Giallonardo, Anna Teresa | |
| A novel GABAergic dysfunction in human Dravet syndrome | 2018 | Ruffolo, Gabriele; Cifelli, Pierangelo; Roseti, Cristina; Thom, Maria; van Vliet, Erwin A.; Limatola, Cristina; Aronica, Eleonora; Palma, Eleonora | |
| A systems-level analysis highlights microglial activation as a modifying factor in common epilepsies | 2022 | Altmann, Andre; Ryten, Mina; Di Nunzio, Martina; Ravizza, Teresa; Tolomeo, Daniele; Reynolds, Regina H; Somani, Alyma; Bacigaluppi, Marco; Iori, Valentina; Micotti, Edoardo; Di Sapia, Rossella; Cerovic, Milica; Palma, Eleonora; Ruffolo, Gabriele; Botía, Juan A; Absil, Julie; Alhusaini, Saud; Alvim, Marina K M; Auvinen, Pia; Bargallo, Nuria; Bartolini, Emanuele; Bender, Benjamin; Bergo, Felipe P G; Bernardes, Tauana; Bernasconi, Andrea; Bernasconi, Neda; Bernhardt, Boris C; Blackmon, Karen; Braga, Barbara; Caligiuri, Maria Eugenia; Calvo, Anna; Carlson, Chad; Carr, Sarah J; Cavalleri, Gianpiero L; Cendes, Fernando; Chen, Jian; Chen, Shuai; Cherubini, Andrea; Concha, Luis; David, Philippe; Delanty, Norman; Depondt, Chantal; Devinsky, Orrin; Doherty, Colin P; Domin, Martin; Focke, Niels K; Foley, Sonya; Franca, Wendy; Gambardella, Antonio; Guerrini, Renzo; Hamandi, Khalid; Hibar, Derrek P; Isaev, Dmitry; Jackson, Graeme D; Jahanshad, Neda; Kalviainen, Reetta; Keller, Simon S; Kochunov, Peter; Kotikalapudi, Raviteja; Kowalczyk, Magdalena A; Kuzniecky, Ruben; Kwan, Patrick; Labate, Angelo; Langner, Soenke; Lenge, Matteo; Liu, Min; Martin, Pascal; Mascalchi, Mario; Meletti, Stefano; Morita-Sherman, Marcia E; O'Brien, Terence J; Pariente, Jose C; Richardson, Mark P; Rodriguez-Cruces, Raul; Rummel, Christian; Saavalainen, Taavi; Semmelroch, Mira K; Severino, Mariasavina; Striano, Pasquale; Thesen, Thomas; Thomas, Rhys H; Tondelli, Manuela; Tortora, Domenico; Vaudano, Anna Elisabetta; Vivash, Lucy; von Podewils, Felix; Wagner, Jan; Weber, Bernd; Wiest, Roland; Yasuda, Clarissa L; Zhang, Guohao; Zhang, Junsong; Leu, Costin; Avbersek, Andreja; Thom, Maria; Whelan, Christopher D; Thompson, Paul; Mcdonald, Carrie R; Vezzani, Annamaria; Sisodiya, Sanjay M | |
| Acetylcholine receptors from human muscle as pharmacological targets for ALS therapy | 2016 | Palma, E.; Reyes-Ruiz, J. M.; Lopergolo, D.; Roseti, C.; Bertollini, C.; Ruffolo, G.; Cifelli, P.; Onesti, E.; Limatola, C.; Miledi, R.; Inghilleri, M. | |
| Acetylcholine receptors from human muscle as pharmacological targets for ALS therapy | 2016 | Palma, Eleonora; Reyes Ruiz, Jorge Mauricio; Lopergolo, Diego; Roseti, Cristina; Bertollini, Cristina; Ruffolo, Gabriele; Cifelli, Pierangelo; Onesti, Emanuela; Limatola, Cristina; Miledi, Ricardo; Inghilleri, Maurizio | |
| An unbalanced synaptic transmission. Cause or consequence of the amyloid oligomers neurotoxicity? | 2021 | Sciaccaluga, M.; Megaro, A.; Bellomo, G.; Ruffolo, G.; Romoli, M.; Palma, E.; Costa, C. | |
| Cannabis in Epilepsy: from clinical practice to basic research focusing on the possible role of cannabidivarin | 2016 | Morano, Alessandra; Cifelli, Pierangelo; Antonilli, Letizia; Fattouch, Jinane; Ruffolo, Gabriele; Aronica, E; Limatola, Cristina; DI BONAVENTURA, Carlo; Giallonardo, Anna Teresa; Nencini, Paolo; Roseti, Cristina; Palma, Eleonora | |
| Classical and Unexpected Effects of Ultra-Micronized {PEA} in Neuromuscular Function | 2022 | Cifelli, Pierangelo; Ruffolo, Gabriele; Ceccanti, Marco; Cambieri, Chiara; Libonati, Laura; Palma, Eleonora; Inghilleri, Maurizio | |
| Dissecting the molecular determinants of GABAA receptors current rundown, a hallmark of refractory human epilepsy | 2021 | Cifelli, Pierangelo; Di Angelantonio, Silvia; Alfano, Veronica; Morano, Alessandra; De Felice, Eleonora; Aronica, Eleonora; Ruffolo, Gabriele; Palma, Eleonora | |
| Editorial: epilepsy and neurodevelopmental diseases | 2020 | Ruffolo, G.; Van Vliet, E. A.; Aronica, E.; Palma, E. | |
| Effects of 3,4-diaminopyridine on myasthenia gravis: Preliminary results of an open-label study | 2022 | Ceccanti, Marco; Libonati, Laura; Ruffolo, Gabriele; Cifelli, Pierangelo; Moret, Federica; Frasca, Vittorio; Palma, Eleonora; Inghilleri, Maurizio; Cambieri, Chiara | |
| Erythropoietin increases GABA a currents in human cortex from TLE patients | 2019 | Roseti, Cristina; Cifelli, Pierangelo; Ruffolo, Gabriele; Barbieri, Elena; Guescini, Michele; Esposito, Vincenzo; Di Gennaro, Giancarlo; Limatola, Cristina; Giovannelli, Aldo; Aronica, Eleonora; Palma, Eleonora | |
| Functional aspects of early brain development are preserved in tuberous sclerosis complex (TSC) epileptogenic lesions | 2016 | Ruffolo, Gabriele; Iyer, Anand; Cifelli, Pierangelo; Roseti, Cristina; Mühlebner, Angelika; van Scheppingen, Jackelien; Scholl, Theresa; Hainfellner, Johannes A.; Feucht, Martha; Krsek, Pavel; Zamecnik, Josef; Jansen, Floor E.; Spliet, Wim G. M.; Limatola, Cristina; Aronica, Eleonora; Palma, Eleonora | |
| Functional Gastrointestinal Disorders in Patients With Epilepsy: Reciprocal Influence and Impact on Seizure Occurrence | 2021 | Avorio, F.; Cerulli Irelli, E.; Morano, A.; Fanella, M.; Orlando, B.; Albini, M.; Basili, L. M.; Ruffolo, G.; Fattouch, J.; Manfredi, M.; Russo, E.; Striano, P.; Carabotti, M.; Giallonardo, A. T.; Severi, C.; Di Bonaventura, C. | |
| GABAA currents are decreased by IL-1β in epileptogenic tissue of patients with temporal lobe epilepsy: implications for ictogenesis | 2015 | Roseti, Cristina; van Vliet, Erwin A; Cifelli, Pierangelo; Ruffolo, Gabriele; Baayen, Johannes C; DI CASTRO, MARIA AMALIA; Bertollini, Cristina; Limatola, Cristina; Aronica, Eleonora; Vezzani, Annamaria; Palma, Eleonora | |
| GABAA receptor function is enhanced by Interleukin-10 in human epileptogenic gangliogliomas and its effect is counteracted by Interleukin-1β | 2022 | Ruffolo, Gabriele; Alfano, Veronica; Romagnolo, Alessia; Zimmer, Till; Mills, James D; Cifelli, Pierangelo; Gaeta, Alessandro; Morano, Alessandra; Anink, Jasper; Mühlebner, Angelika; Vezzani, Annamaria; Aronica, Eleonora; Palma, Eleonora | |
| GABAergic neurotransmission in human tissues is modulated by cannabidiol | 2022 | Ruffolo, Gabriele; Gaeta, Alessandro; Cannata, Beatrice; Pinzaglia, Camilla; Aronica, Eleonora; Morano, Alessandra; Cifelli, Pierangelo; Palma, Eleonora | |
| Human iPSC Modeling of Genetic Febrile Seizure Reveals Aberrant Molecular and Physiological Features Underlying an Impaired Neuronal Activity | 2022 | Scalise, Stefania; Zannino, Clara; Lucchino, Valeria; Lo Conte, Michela; Scaramuzzino, Luana; Cifelli, Pierangelo; D'Andrea, Tiziano; Martinello, Katiuscia; Fucile, Sergio; Palma, Eleonora; Gambardella, Antonio; Ruffolo, Gabriele; Cuda, Giovanni; Immacolata Parrotta, Elvira | |
| Immune-mediated myogenesis and acetylcholine receptor clustering promote a slow disease progression in ALS mouse models | 2023 | Margotta, Cassandra; Fabbrizio, Paola; Ceccanti, Marco; Cambieri, Chiara; Ruffolo, Gabriele; D'Agostino, Jessica; Trolese, Maria Chiara; Cifelli, Pierangelo; Alfano, Veronica; Laurini, Christian; Scaricamazza, Silvia; Ferri, Alberto; Sorarù, Gianni; Palma, Eleonora; Inghilleri, Maurizio; Bendotti, Caterina; Nardo, Giovanni | |
| Impaired GABAergic regulation and developmental immaturity in interneurons derived from the medial ganglionic eminence in the tuberous sclerosis complex | 2024 | Scheper, M.; Sorensen, F. N. F.; Ruffolo, G.; Gaeta, A.; Lissner, L. J.; Anink, J. J.; Korshunova, I.; Jansen, F. E.; Riney, K.; van Hecke, W.; Muhlebner, A.; Khodosevich, K.; Schubert, D.; Palma, E.; Mills, J. D.; Aronica, E. |