We explored the spatial distribution of human Y chromosomal diversity on a microgeographic scale, by typing 30 population samples from closely spaced locations in Italy and Greece for 9 haplogroups and their internal microsatellite variation. We confirm a significant difference in the composition of the Y chromosomal gene pools of the two countries. However, within each country, heterogeneity is not organized along the lines of clinal variation deduced from studies on larger spatial scales. Microsatellite data indicate that local increases of haplogroup frequencies can be often explained by a limited number of founders. We conclude that local founder or drift effects are the main determinants in shaping the microgeographic Y chromosomal diversity.
Clinal patterns of human chromosomal diversity in continental Italy and Greece are dominated by drift and founder effect / DI GIACOMO, F; Luca, F; Anagnou, N; Ciavarella, G; Corbo, Rosa Maria; Cresta, M; Cucci, F; DI STASI, L; Agostiano, V; Giparaki, M; Loutradis, A; Mammi', C; Michalodimitrakis, En; Papola, F; Pedicini, G; Plata, E; Terrenato, L; Tofanelli, S; Malaspina, P; Novelletto,. - In: MOLECULAR PHYLOGENETICS AND EVOLUTION. - ISSN 1055-7903. - STAMPA. - 28:(2003), pp. 387-395. [10.1016/S1055-7903(03)00016-2]
Clinal patterns of human chromosomal diversity in continental Italy and Greece are dominated by drift and founder effect
CORBO, Rosa Maria;
2003
Abstract
We explored the spatial distribution of human Y chromosomal diversity on a microgeographic scale, by typing 30 population samples from closely spaced locations in Italy and Greece for 9 haplogroups and their internal microsatellite variation. We confirm a significant difference in the composition of the Y chromosomal gene pools of the two countries. However, within each country, heterogeneity is not organized along the lines of clinal variation deduced from studies on larger spatial scales. Microsatellite data indicate that local increases of haplogroup frequencies can be often explained by a limited number of founders. We conclude that local founder or drift effects are the main determinants in shaping the microgeographic Y chromosomal diversity.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.