FlexServ is a web-based tool for the analysis of protein flexibility. The server incorporates powerful protocols for the coarse-grained determination of protein dynamics using different versions of Normal Mode Analysis (NMA), Brownian dynamics (BD) and Discrete Dynamics (DMD). It can also analyze user provided trajectories. The server allows a complete analysis of flexibility using a large variety of metrics, including basic geometrical analysis, B-factors, essential dynamics, stiffness analysis, collectivity measures, Lindemann's indexes, residue correlation, chain-correlations, dynamic domain determination, hinge point detections, etc. Data is presented through a web interface as plain text, 2D and 3D graphics.
FlexServ: An integrated tool for the analysis of protein flexibility / Camps, Jordi; Carrillo, Oliver; Emperador, Agustí; Orellana, Laura; Hospital, Adam; Rueda, Manuel; Cicin Sain, Damjan; D'Abramo, Marco; Gelpí, Josep Lluís; Orozco, Modesto. - In: BIOINFORMATICS. - ISSN 1367-4803. - 25:13(2009), pp. 1709-1710. [10.1093/bioinformatics/btp304]
FlexServ: An integrated tool for the analysis of protein flexibility
D'ABRAMO, Marco;
2009
Abstract
FlexServ is a web-based tool for the analysis of protein flexibility. The server incorporates powerful protocols for the coarse-grained determination of protein dynamics using different versions of Normal Mode Analysis (NMA), Brownian dynamics (BD) and Discrete Dynamics (DMD). It can also analyze user provided trajectories. The server allows a complete analysis of flexibility using a large variety of metrics, including basic geometrical analysis, B-factors, essential dynamics, stiffness analysis, collectivity measures, Lindemann's indexes, residue correlation, chain-correlations, dynamic domain determination, hinge point detections, etc. Data is presented through a web interface as plain text, 2D and 3D graphics.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
