Cortical plasticity effects on motor or somatosensory cortex are induced by the Paired Associative Stimulation (PAS) protocol, and long-term potentiation (LTP) - depression (LTD) mechanisms were proposed on the basis of independent evidences. PAS consists of pairing a repetitive peripheral electrical stimulation with cortical Transcranial Magnetic Stimulation (TMS). The effects of this protocol on motor or somatosensory cortex are valuable by changes in amplitude of motor evoked potentials (Stefan et al., 2000) or somatosensory evoked potentials (Wolters et al., 2005; Litvak et al., 2007), respectively. Since age-dependent effects have been shown for motor cortical plasticity (Tecchio et al., 2008; Florian et al., 2008), the aim of the present study is to investigate the same effects in somatosensory cortex.
Plasticity in primary somatosensory cortex in young and older humans / Pellicciari, M. C.; Rosato, M.; Miniussi, C.; Rossini, P. M.; DE GENNARO, Luigi. - In: BRAIN STIMULATION. - ISSN 1935-861X. - STAMPA. - 1:(2008), p. 266. (Intervento presentato al convegno Third International Conference on Transcranial Magnetic and Direct Current Stimulation Program tenutosi a Gottingen) [10.1016/j.brs.2008.06.011].
Plasticity in primary somatosensory cortex in young and older humans
DE GENNARO, Luigi
2008
Abstract
Cortical plasticity effects on motor or somatosensory cortex are induced by the Paired Associative Stimulation (PAS) protocol, and long-term potentiation (LTP) - depression (LTD) mechanisms were proposed on the basis of independent evidences. PAS consists of pairing a repetitive peripheral electrical stimulation with cortical Transcranial Magnetic Stimulation (TMS). The effects of this protocol on motor or somatosensory cortex are valuable by changes in amplitude of motor evoked potentials (Stefan et al., 2000) or somatosensory evoked potentials (Wolters et al., 2005; Litvak et al., 2007), respectively. Since age-dependent effects have been shown for motor cortical plasticity (Tecchio et al., 2008; Florian et al., 2008), the aim of the present study is to investigate the same effects in somatosensory cortex.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
