The best therapy regimen for refractory obstetrical antiphospholipid syndrome remains to be determined. Additional treatments with steroids, plasma exchanges and immunoglobulins failed to show any beneficial effect. We present a case of a woman who had a better pregnancy outcome after the administration of hydroxychloroquine (HCQ) as additional treatment. Furthermore, we highlighted that HCQ was able to dramatically reduce the antiphospholipid antibodies levels.

Is there any role for the hydroxychloroquine (HCQ) in refractory obstetrical antiphospholipid syndrome (APS) treatment? / De Carolis, S; Botta, A.; Salvi, S.; di Pasquo, E.; Del Sordo, G.; Garufi, Cristina; Lanzone, A.; De Carolis, M. P.. - In: AUTOIMMUNITY REVIEWS. - ISSN 1568-9972. - ELETTRONICO. - 14:9(2015), pp. 760-762. [10.1016/j.autrev.2015.04.010]

Is there any role for the hydroxychloroquine (HCQ) in refractory obstetrical antiphospholipid syndrome (APS) treatment?

GARUFI, CRISTINA;
2015

Abstract

The best therapy regimen for refractory obstetrical antiphospholipid syndrome remains to be determined. Additional treatments with steroids, plasma exchanges and immunoglobulins failed to show any beneficial effect. We present a case of a woman who had a better pregnancy outcome after the administration of hydroxychloroquine (HCQ) as additional treatment. Furthermore, we highlighted that HCQ was able to dramatically reduce the antiphospholipid antibodies levels.
2015
Adult; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Female; Humans; Hydroxychloroquine; Phenotype; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Immunology; Immunology and Allergy; Medicine (all)
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Is there any role for the hydroxychloroquine (HCQ) in refractory obstetrical antiphospholipid syndrome (APS) treatment? / De Carolis, S; Botta, A.; Salvi, S.; di Pasquo, E.; Del Sordo, G.; Garufi, Cristina; Lanzone, A.; De Carolis, M. P.. - In: AUTOIMMUNITY REVIEWS. - ISSN 1568-9972. - ELETTRONICO. - 14:9(2015), pp. 760-762. [10.1016/j.autrev.2015.04.010]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/975383
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