In Parkinson's disease (PD), the influence of chronic pain on motor features has never been investigated. We have recently designed a technique that combines nociceptive system activation by laser stimuli and primary motor cortex (M1) activation through transcranial magnetic stimulation (TMS), in a laser-paired associative stimulation design (Laser-PAS). In controls, Laser-PAS induces long-term changes in motor evoked potentials reflecting M1 long-term potentiation-like plasticity, arising from pain-motor integration.

Pain-motor integration in the primary motor cortex in Parkinson's disease / Suppa, Antonio; Leone, Caterina; DI STASIO, Flavio; Marsili, Luca; Di Santo, A; Biasiotta, A; LA CESA, Silvia; Truini, Andrea; Cruccu, Giorgio; Berardelli, Alfredo. - In: BRAIN STIMULATION. - ISSN 1935-861X. - (2017), pp. 806-816. [10.1016/j.brs.2017.04.130]

Pain-motor integration in the primary motor cortex in Parkinson's disease

SUPPA, ANTONIO;LEONE, CATERINA;DI STASIO, FLAVIO;MARSILI, LUCA;Di Santo, A;LA CESA, SILVIA;TRUINI, ANDREA;CRUCCU, Giorgio;BERARDELLI, Alfredo
2017

Abstract

In Parkinson's disease (PD), the influence of chronic pain on motor features has never been investigated. We have recently designed a technique that combines nociceptive system activation by laser stimuli and primary motor cortex (M1) activation through transcranial magnetic stimulation (TMS), in a laser-paired associative stimulation design (Laser-PAS). In controls, Laser-PAS induces long-term changes in motor evoked potentials reflecting M1 long-term potentiation-like plasticity, arising from pain-motor integration.
2017
laser-evoked potentials; pain-motor integration; paired associative stimulation; Parkinson's disease; primary motor cortex
01 Pubblicazione su rivista::01a Articolo in rivista
Pain-motor integration in the primary motor cortex in Parkinson's disease / Suppa, Antonio; Leone, Caterina; DI STASIO, Flavio; Marsili, Luca; Di Santo, A; Biasiotta, A; LA CESA, Silvia; Truini, Andrea; Cruccu, Giorgio; Berardelli, Alfredo. - In: BRAIN STIMULATION. - ISSN 1935-861X. - (2017), pp. 806-816. [10.1016/j.brs.2017.04.130]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/967144
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