Patients with peripheral neuropathic pain (NP) may only achieve partial pain relief with currently recommended first-line oral treatments, which are also associated with systemic adverse events. Topical treatments are currently considered second- or third-line options, but a recent pharmacologic treatment algorithm has called for broader first-line use of these agents. This has highlighted a need to communicate the benefits associated with topical agents, in particular around the efficacy, targeted local action, and limited systemic availability resulting in minimal systemic adverse events and drug-drug interactions.

Topical treatment of peripheral neuropathic pain: applying the evidence / Sommer, Claudia; Cruccu, Giorgio. - In: JOURNAL OF PAIN AND SYMPTOM MANAGEMENT. - ISSN 0885-3924. - 53:3(2017), pp. 614-629. [10.1016/j.jpainsymman.2016.09.015]

Topical treatment of peripheral neuropathic pain: applying the evidence

CRUCCU, Giorgio
2017

Abstract

Patients with peripheral neuropathic pain (NP) may only achieve partial pain relief with currently recommended first-line oral treatments, which are also associated with systemic adverse events. Topical treatments are currently considered second- or third-line options, but a recent pharmacologic treatment algorithm has called for broader first-line use of these agents. This has highlighted a need to communicate the benefits associated with topical agents, in particular around the efficacy, targeted local action, and limited systemic availability resulting in minimal systemic adverse events and drug-drug interactions.
2017
Peripheral neuropathic pain; capsaicin 8% patch; lidocaine 5% medicated plaster; topical
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Topical treatment of peripheral neuropathic pain: applying the evidence / Sommer, Claudia; Cruccu, Giorgio. - In: JOURNAL OF PAIN AND SYMPTOM MANAGEMENT. - ISSN 0885-3924. - 53:3(2017), pp. 614-629. [10.1016/j.jpainsymman.2016.09.015]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/967140
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