The biochemistry underlying the physiological, adaptive, and toxic effects of carbon monoxide (CO) is linked to its affinity for reduced transition metals. We investigated CO signaling in the vasculature, where hemoglobin (Hb), the CO most important metal-containing carrier is highly concentrated inside red blood cells (RBCs).

Carbon monoxide signaling in human red blood cells: evidence for pentose phosphate pathway activation and protein deglutathionylation / Metere, Alessio; Iorio, Egidio; Scorza, Giuseppe; Camerini, Serena; Casella, Marialuisa; Crescenzi, Marco; Minetti, Maurizio; Pietraforte, Donatella. - In: ANTIOXIDANTS & REDOX SIGNALING. - ISSN 1523-0864. - 20:3(2014), pp. 403-16-416. [10.1089/ars.2012.5102]

Carbon monoxide signaling in human red blood cells: evidence for pentose phosphate pathway activation and protein deglutathionylation

METERE, ALESSIO;IORIO, Egidio;
2014

Abstract

The biochemistry underlying the physiological, adaptive, and toxic effects of carbon monoxide (CO) is linked to its affinity for reduced transition metals. We investigated CO signaling in the vasculature, where hemoglobin (Hb), the CO most important metal-containing carrier is highly concentrated inside red blood cells (RBCs).
2014
Carbon Monoxide; Cytosol; Erythrocytes; Gene Expression; Glutathione; Glutathione Disulfide; Hemoglobins; Humans; Oxidative Stress; Pentose Phosphate Pathway; Signal Transduction
01 Pubblicazione su rivista::01a Articolo in rivista
Carbon monoxide signaling in human red blood cells: evidence for pentose phosphate pathway activation and protein deglutathionylation / Metere, Alessio; Iorio, Egidio; Scorza, Giuseppe; Camerini, Serena; Casella, Marialuisa; Crescenzi, Marco; Minetti, Maurizio; Pietraforte, Donatella. - In: ANTIOXIDANTS & REDOX SIGNALING. - ISSN 1523-0864. - 20:3(2014), pp. 403-16-416. [10.1089/ars.2012.5102]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/965689
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