Coriander (Coriandrum sativum L., Apiaceae) is known for its antimicrobial activity and the aim of this study was to investigate the effect of its essential oil (CDO) against multidrug resistant uropathogenic Escherichia coli (UPEC). CDO was able to inhibit the growth of UPEC strains and propidium iodide uptake, and electron microscopy examination suggested that bacterial structural modifications occurred. The presence of CDO reduced the MIC of gentamicin. E.coli adhesion efficiency on cell monolayers and abiotic surfaces was not affected by subMIC oil concentrations; furthermore, CDO showed cytotoxic activity towards the HEp-2 tumor cell line. These findings contribute to the knowledge about essential oils as sources of potential antimicrobial agents against uropathogenic E. coli and encourage further investigations.

Coriander (Coriandrum sativum) essential oil: effect on multidrug resistant uropathogenic Escherichia coli / Scazzocchio, Francesca; Mondi', Lorenzo; Ammendolia, Maria Grazia; Goldoni, Paola; Comanducci, Antonella; Marazzato, Massimiliano; Conte, Maria Pia; Rinaldi, Federica; Crestoni, Maria Elisa; Fraschetti, Caterina; Longhi, Catia. - In: NATURAL PRODUCT COMMUNICATIONS. - ISSN 1555-9475. - STAMPA. - 12:4(2017), pp. 623-626.

Coriander (Coriandrum sativum) essential oil: effect on multidrug resistant uropathogenic Escherichia coli

SCAZZOCCHIO, Francesca;MONDI', Lorenzo;AMMENDOLIA, Maria Grazia;GOLDONI, Paola;COMANDUCCI, Antonella;Marazzato, Massimiliano;CONTE, Maria Pia;RINALDI, FEDERICA;CRESTONI, Maria Elisa;FRASCHETTI, CATERINA;LONGHI, Catia
2017

Abstract

Coriander (Coriandrum sativum L., Apiaceae) is known for its antimicrobial activity and the aim of this study was to investigate the effect of its essential oil (CDO) against multidrug resistant uropathogenic Escherichia coli (UPEC). CDO was able to inhibit the growth of UPEC strains and propidium iodide uptake, and electron microscopy examination suggested that bacterial structural modifications occurred. The presence of CDO reduced the MIC of gentamicin. E.coli adhesion efficiency on cell monolayers and abiotic surfaces was not affected by subMIC oil concentrations; furthermore, CDO showed cytotoxic activity towards the HEp-2 tumor cell line. These findings contribute to the knowledge about essential oils as sources of potential antimicrobial agents against uropathogenic E. coli and encourage further investigations.
2017
coriandrum sativum; escherichia coli; uropathogenic escherichia coli; essential oil; antibiotic resistance; urinary tract infections
01 Pubblicazione su rivista::01a Articolo in rivista
Coriander (Coriandrum sativum) essential oil: effect on multidrug resistant uropathogenic Escherichia coli / Scazzocchio, Francesca; Mondi', Lorenzo; Ammendolia, Maria Grazia; Goldoni, Paola; Comanducci, Antonella; Marazzato, Massimiliano; Conte, Maria Pia; Rinaldi, Federica; Crestoni, Maria Elisa; Fraschetti, Caterina; Longhi, Catia. - In: NATURAL PRODUCT COMMUNICATIONS. - ISSN 1555-9475. - STAMPA. - 12:4(2017), pp. 623-626.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/963638
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