Recent findings suggest that an imbalance of Th1, Th2 and Treg plays a critical role in the pathogenesis of AD and that CD8+ T cells are required for the development of AD lesions.[1, 2] We studied the phenotype of peripheral blood (PB) circulating and intraepithelial lymphocytes deriving from skin affected by chronic moderate–severe AD, acute reaction induced by an atopy patch test to Dermatophagoides spp (Dmix/APT) and in skin spared by AD.

Atopic dermatitis IL17A- and IFN-γ-producing lymphocytes: Investigation in blood, chronic lesions and APT / Grieco, Teresa; Faina, Valentina; Porzia, Alessandra; Paolino, Giovanni; Morrone, Stefania; Bottoni, Ugo; Calvieri, Stefano; Mainiero, Fabrizio. - In: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. - ISSN 0926-9959. - (2017). [10.1111/jdv.14258]

Atopic dermatitis IL17A- and IFN-γ-producing lymphocytes: Investigation in blood, chronic lesions and APT

GRIECO, Teresa;FAINA, VALENTINA;PORZIA, Alessandra;paolino, giovanni;MORRONE, Stefania;BOTTONI, Ugo;CALVIERI, Stefano;MAINIERO, Fabrizio
2017

Abstract

Recent findings suggest that an imbalance of Th1, Th2 and Treg plays a critical role in the pathogenesis of AD and that CD8+ T cells are required for the development of AD lesions.[1, 2] We studied the phenotype of peripheral blood (PB) circulating and intraepithelial lymphocytes deriving from skin affected by chronic moderate–severe AD, acute reaction induced by an atopy patch test to Dermatophagoides spp (Dmix/APT) and in skin spared by AD.
File allegati a questo prodotto
File Dimensione Formato  
Grieco_atopic-dermatitis_2018.pdf

solo gestori archivio

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 140.83 kB
Formato Adobe PDF
140.83 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/962894
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 3
  • ???jsp.display-item.citation.isi??? 3
social impact