channel over multiple bursts (the absolute TOA method). For homogeneous gels the relative method provided shear-wave speed with acceptable precision and accuracy when judged against the expected linear dependence of shear modulus on gelatine concentration (R2 = 0.95) and ultimate resolution capabilities limited by 184μm inter-channel distance. This overall approach shows promise for its eventual provision as a research tool in cancer cell biology. Further work is required to optimize parameters such as vibration frequency, burst length and amplitude, and to assess the lateral and axial resolutions of this type of device as well as to create 3D elastograms..
Multi-channel optical coherence elastography using relative and absolute shear-wave time of flight / Elyas, Eli; Grimwood, Alex; Erler, Janine T.; Robinson, Simon P.; Cox, Thomas R.; Woods, Daniel; Clowes, Peter; DE LUCA, Ramona; Marinozzi, Franco; Fromageau, Jérémie; Bamber, Jeffrey C.. - In: PLOS ONE. - ISSN 1932-6203. - 12:1(2017). [10.1371/journal.pone.0169664]
Multi-channel optical coherence elastography using relative and absolute shear-wave time of flight
DE LUCA, RAMONA;MARINOZZI, Franco;
2017
Abstract
channel over multiple bursts (the absolute TOA method). For homogeneous gels the relative method provided shear-wave speed with acceptable precision and accuracy when judged against the expected linear dependence of shear modulus on gelatine concentration (R2 = 0.95) and ultimate resolution capabilities limited by 184μm inter-channel distance. This overall approach shows promise for its eventual provision as a research tool in cancer cell biology. Further work is required to optimize parameters such as vibration frequency, burst length and amplitude, and to assess the lateral and axial resolutions of this type of device as well as to create 3D elastograms..| File | Dimensione | Formato | |
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