The estimation of space and time can interfere with each other, and neuroimaging studies have shown overlapping activation in the parietal and prefrontal cortical areas. We used duration and distance discrimination tasks to determine whether space and time share resources in prefrontal cortex (PF) neurons. Monkeys were required to report which of two stimuli, a red circle or blue square, presented sequentially, were longer and farther, respectively, in the duration and distance tasks. In a previous study, we showed that relative duration and distance are coded by different populations of neurons and that the only common representation is related to goal coding. Here, we examined the coding of absolute duration and distance. Our results support a model of independent coding of absolute duration and distance metrics by demonstrating that not only relative magnitude but also absolute magnitude are independently coded in the PF.

Independent coding of absolute duration and distance magnitudes in the prefrontal cortex / Marcos, Encarni; Tsujimoto, Satoshi; Genovesio, Aldo. - In: JOURNAL OF NEUROPHYSIOLOGY. - ISSN 0022-3077. - STAMPA. - 117:1(2017), pp. 195-203. [10.1152/jn.00245.2016]

Independent coding of absolute duration and distance magnitudes in the prefrontal cortex

GENOVESIO, Aldo
2017

Abstract

The estimation of space and time can interfere with each other, and neuroimaging studies have shown overlapping activation in the parietal and prefrontal cortical areas. We used duration and distance discrimination tasks to determine whether space and time share resources in prefrontal cortex (PF) neurons. Monkeys were required to report which of two stimuli, a red circle or blue square, presented sequentially, were longer and farther, respectively, in the duration and distance tasks. In a previous study, we showed that relative duration and distance are coded by different populations of neurons and that the only common representation is related to goal coding. Here, we examined the coding of absolute duration and distance. Our results support a model of independent coding of absolute duration and distance metrics by demonstrating that not only relative magnitude but also absolute magnitude are independently coded in the PF.
2017
magnitude; monkey; prefrontal; spatial; timing; neuroscience (all); physiology
01 Pubblicazione su rivista::01a Articolo in rivista
Independent coding of absolute duration and distance magnitudes in the prefrontal cortex / Marcos, Encarni; Tsujimoto, Satoshi; Genovesio, Aldo. - In: JOURNAL OF NEUROPHYSIOLOGY. - ISSN 0022-3077. - STAMPA. - 117:1(2017), pp. 195-203. [10.1152/jn.00245.2016]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/955473
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