Eosinophilic cytoplasmic inclusions in dopaminergic nigrostria-tal neurons, the primary component of which isa-synuclein, arethe pathological hallmark of Parkinson's disease (PD)[1]. Nervefi-bers immunoreactive to phosphorylateda-synuclein have beenidentified inpostmortem[2]andin vivo[3]submandibular gland bi-opsy from PD patients. Here we measured phosphorylated-a-synu-clein immunoreactivity in nervefibers from minor salivary glandbiopsy in PD. The study was approved by the“Sapienza”UniversityEthical Committee.
Phosphorylated α-synuclein immunoreactivity in nerve fibers from minor salivary glands in Parkinson's disease / Carletti, R; Campo, Flaminia; Fusconi, Massimo; Pellicano, Clelia; De Vincentiis, Marco; Pontieri, Francesco Ernesto; Di Gioia, Cira Rosaria Tiziana. - In: PARKINSONISM & RELATED DISORDERS. - ISSN 1353-8020. - STAMPA. - 38:(2017), pp. 99-101. [10.1016/j.parkreldis.2017.02.031]
Phosphorylated α-synuclein immunoreactivity in nerve fibers from minor salivary glands in Parkinson's disease
Carletti, RPrimo
;CAMPO, FLAMINIASecondo
;FUSCONI, Massimo;PELLICANO, CLELIA;DE VINCENTIIS, Marco;PONTIERI, FRANCESCO ERNESTOPenultimo
;DI GIOIA, Cira Rosaria Tiziana
Ultimo
2017
Abstract
Eosinophilic cytoplasmic inclusions in dopaminergic nigrostria-tal neurons, the primary component of which isa-synuclein, arethe pathological hallmark of Parkinson's disease (PD)[1]. Nervefi-bers immunoreactive to phosphorylateda-synuclein have beenidentified inpostmortem[2]andin vivo[3]submandibular gland bi-opsy from PD patients. Here we measured phosphorylated-a-synu-clein immunoreactivity in nervefibers from minor salivary glandbiopsy in PD. The study was approved by the“Sapienza”UniversityEthical Committee.| File | Dimensione | Formato | |
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