Eosinophilic cytoplasmic inclusions in dopaminergic nigrostria-tal neurons, the primary component of which isa-synuclein, arethe pathological hallmark of Parkinson's disease (PD)[1]. Nervefi-bers immunoreactive to phosphorylateda-synuclein have beenidentified inpostmortem[2]andin vivo[3]submandibular gland bi-opsy from PD patients. Here we measured phosphorylated-a-synu-clein immunoreactivity in nervefibers from minor salivary glandbiopsy in PD. The study was approved by the“Sapienza”UniversityEthical Committee.

Phosphorylated α-synuclein immunoreactivity in nerve fibers from minor salivary glands in Parkinson's disease / Carletti, R; Campo, Flaminia; Fusconi, Massimo; Pellicano, Clelia; De Vincentiis, Marco; Pontieri, Francesco Ernesto; Di Gioia, Cira Rosaria Tiziana. - In: PARKINSONISM & RELATED DISORDERS. - ISSN 1353-8020. - STAMPA. - 38(2017), pp. 99-101. [10.1016/j.parkreldis.2017.02.031]

Phosphorylated α-synuclein immunoreactivity in nerve fibers from minor salivary glands in Parkinson's disease

Carletti, R
Primo
;
CAMPO, FLAMINIA
Secondo
;
FUSCONI, Massimo;PELLICANO, CLELIA;DE VINCENTIIS, Marco;PONTIERI, FRANCESCO ERNESTO
Penultimo
;
DI GIOIA, Cira Rosaria Tiziana
Ultimo
2017

Abstract

Eosinophilic cytoplasmic inclusions in dopaminergic nigrostria-tal neurons, the primary component of which isa-synuclein, arethe pathological hallmark of Parkinson's disease (PD)[1]. Nervefi-bers immunoreactive to phosphorylateda-synuclein have beenidentified inpostmortem[2]andin vivo[3]submandibular gland bi-opsy from PD patients. Here we measured phosphorylated-a-synu-clein immunoreactivity in nervefibers from minor salivary glandbiopsy in PD. The study was approved by the“Sapienza”UniversityEthical Committee.
File allegati a questo prodotto
File Dimensione Formato  
Carletti_Phosphorylated_2017_pp.pdf

solo gestori archivio

Note: articolo principale
Tipologia: Documento in Post-print (versione successiva alla peer review e accettata per la pubblicazione)
Licenza: Creative commons
Dimensione 683.88 kB
Formato Adobe PDF
683.88 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Carletti_Phosphorylated_2017.pdf

solo gestori archivio

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 608.13 kB
Formato Adobe PDF
608.13 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11573/954557
Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus 9
  • ???jsp.display-item.citation.isi??? 9
social impact