Molecular medicine is founded on the synergy between Chemistry, Physics, Biology and Medicine, with the ambitious goal of tackling diseases from a molecular perspective. This Review aims at retracing a personal outlook of the birth and development of molecular medicine, as well as at highlighting some of the most urgent challenges linked to aging and represented by incurable neurodegenerative diseases caused by protein misfolding. Furthermore, we emphasize the emerging role of the retromer dysfunctions and improper protein sorting in Alzheimer's disease and other important neurological disordered

Molecular medicine - to be or not to be / Brunori, Maurizio; Gianni, Stefano. - In: BIOPHYSICAL CHEMISTRY. - ISSN 0301-4622. - 214-215:(2016), pp. 33-46. [10.1016/j.bpc.2016.05.004]

Molecular medicine - to be or not to be

BRUNORI, Maurizio
;
GIANNI, STEFANO
2016

Abstract

Molecular medicine is founded on the synergy between Chemistry, Physics, Biology and Medicine, with the ambitious goal of tackling diseases from a molecular perspective. This Review aims at retracing a personal outlook of the birth and development of molecular medicine, as well as at highlighting some of the most urgent challenges linked to aging and represented by incurable neurodegenerative diseases caused by protein misfolding. Furthermore, we emphasize the emerging role of the retromer dysfunctions and improper protein sorting in Alzheimer's disease and other important neurological disordered
2016
Protein structure; protein misfolding diseases; drug design; hemoglobin; prions; Alzheimer's disease; retromer
01 Pubblicazione su rivista::01a Articolo in rivista
Molecular medicine - to be or not to be / Brunori, Maurizio; Gianni, Stefano. - In: BIOPHYSICAL CHEMISTRY. - ISSN 0301-4622. - 214-215:(2016), pp. 33-46. [10.1016/j.bpc.2016.05.004]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/954032
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