We have previously shown that in seven drug-resistant epilepsy patients, both reachinggrasping of objects and the mere observation of those actions did desynchronize subdural electrocorticographic (ECoG) alpha (8–13 Hz) and beta (14–30) rhythms as a sign of cortical activation in primary somatosensory-motor, lateral premotor and ventral prefrontal areas (Babiloni et al., 2016a). Furthermore, that desynchronization was greater during action execution than during its observation. In the present exploratory study, we reanalyzed those ECoG data to evaluate the proof-of-concept that lagged linear connectivity (LLC) between primary somatosensory-motor, lateral premotor and ventral prefrontal areas would be enhanced during the action execution compared to the mere observation due to a greater flow of visual and somatomotor information. Results showed that the delta-theta (<8 Hz) LLC between lateral premotor and ventral prefrontal areas was higher during action execution than during action observation. Furthermore, the phase of these delta-theta rhythms entrained the local event-related connectivity of alpha and beta rhythms. It was speculated the existence of a multioscillatory functional network between high-order frontal motor areas which should be more involved during the actual reaching-grasping of objects compared to its mere observation. Future studies in a larger population should cross-validate these preliminary results.

Frontal functional connectivity of electrocorticographic delta and theta rhythms during action execution versus action observation in humans / Babiloni, Claudio; DEL PERCIO, Claudio; Lopez, Susanna; Di Gennaro, Giancarlo; Quarato, Pier P.; Pavone, Luigi; Morace, Roberta; Soricelli, Andrea; Noce, Giuseppe; Esposito, Vincenzo; Gallese, Vittorio; Mirabella, Giovanni. - In: FRONTIERS IN BEHAVIORAL NEUROSCIENCE. - ISSN 1662-5153. - ELETTRONICO. - 11:(2017), pp. 1-11. [10.3389/fnbeh.2017.00020]

Frontal functional connectivity of electrocorticographic delta and theta rhythms during action execution versus action observation in humans

BABILONI, CLAUDIO;DEL PERCIO, CLAUDIO;LOPEZ, SUSANNA;MORACE, ROBERTA;NOCE, GIUSEPPE;ESPOSITO, Vincenzo;Gallese, Vittorio;MIRABELLA, GIOVANNI
2017

Abstract

We have previously shown that in seven drug-resistant epilepsy patients, both reachinggrasping of objects and the mere observation of those actions did desynchronize subdural electrocorticographic (ECoG) alpha (8–13 Hz) and beta (14–30) rhythms as a sign of cortical activation in primary somatosensory-motor, lateral premotor and ventral prefrontal areas (Babiloni et al., 2016a). Furthermore, that desynchronization was greater during action execution than during its observation. In the present exploratory study, we reanalyzed those ECoG data to evaluate the proof-of-concept that lagged linear connectivity (LLC) between primary somatosensory-motor, lateral premotor and ventral prefrontal areas would be enhanced during the action execution compared to the mere observation due to a greater flow of visual and somatomotor information. Results showed that the delta-theta (<8 Hz) LLC between lateral premotor and ventral prefrontal areas was higher during action execution than during action observation. Furthermore, the phase of these delta-theta rhythms entrained the local event-related connectivity of alpha and beta rhythms. It was speculated the existence of a multioscillatory functional network between high-order frontal motor areas which should be more involved during the actual reaching-grasping of objects compared to its mere observation. Future studies in a larger population should cross-validate these preliminary results.
2017
exact low-resolution brain electromagnetic tomography (eLORETA); frontal cortex; lagged linear connectivity; mirror neuron system; movement execution; movement observation; subdural electrocorticography (ECoG); neuropsychology and physiological psychology; cognitive neuroscience; behavioral neuroscience
01 Pubblicazione su rivista::01a Articolo in rivista
Frontal functional connectivity of electrocorticographic delta and theta rhythms during action execution versus action observation in humans / Babiloni, Claudio; DEL PERCIO, Claudio; Lopez, Susanna; Di Gennaro, Giancarlo; Quarato, Pier P.; Pavone, Luigi; Morace, Roberta; Soricelli, Andrea; Noce, Giuseppe; Esposito, Vincenzo; Gallese, Vittorio; Mirabella, Giovanni. - In: FRONTIERS IN BEHAVIORAL NEUROSCIENCE. - ISSN 1662-5153. - ELETTRONICO. - 11:(2017), pp. 1-11. [10.3389/fnbeh.2017.00020]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/953797
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