HIV infection is characterized by a persistent immune activation associated to a compromised gut barrier immunity and alterations in the profile of the fecal flora linked with the progression of inflammatory symptoms. The effects of high concentration multistrain probiotic (Vivomixx®, Viale del Policlinico 155, Rome, Italy in EU; Visbiome®, Dupont, Madison, Wisconsin in USA) on several aspects of intestinal immunity in ART-experienced HIV-1 patients was evaluated.
Probiotic supplementation promotes a reduction in T-cell activation, an increase in Th17 frequencies, and a recovery of intestinal epithelium integrity and mitochondrial morphology in ART-treated HIV-1-positive patients / D'Ettorre, Gabriella; Rossi, Giacomo; Scagnolari, Carolina; Andreotti, Mauro; Giustini, Noemi; Serafino, Sara; Schietroma, Ivan; Corano Scheri, Giuseppe; Fard, Saeid Najafi; Trinchieri, Vito; Mastromarino, Paola; Selvaggi, Carla; Scarpona, Silvia; Fanello, Gianfranco; Fiocca, Fausto; Ceccarelli, Giancarlo; Antonelli, Guido; Brenchley, Jason M; Vullo, Vincenzo. - In: IMMUNITY, INFLAMMATION AND DISEASE. - ISSN 2050-4527. - ELETTRONICO. - 5:3(2017), pp. 244-260. [10.1002/iid3.160]
Probiotic supplementation promotes a reduction in T-cell activation, an increase in Th17 frequencies, and a recovery of intestinal epithelium integrity and mitochondrial morphology in ART-treated HIV-1-positive patients
D'Ettorre, Gabriella;Scagnolari, Carolina;Andreotti, Mauro;Giustini, Noemi;Serafino, Sara;Corano Scheri, Giuseppe;Fard, Saeid Najafi;Trinchieri, Vito;Mastromarino, Paola;Selvaggi, Carla;Fanello, Gianfranco;Fiocca, Fausto;Ceccarelli, Giancarlo;Antonelli, Guido;Vullo, Vincenzo
2017
Abstract
HIV infection is characterized by a persistent immune activation associated to a compromised gut barrier immunity and alterations in the profile of the fecal flora linked with the progression of inflammatory symptoms. The effects of high concentration multistrain probiotic (Vivomixx®, Viale del Policlinico 155, Rome, Italy in EU; Visbiome®, Dupont, Madison, Wisconsin in USA) on several aspects of intestinal immunity in ART-experienced HIV-1 patients was evaluated.| File | Dimensione | Formato | |
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D'Ettorre_Probiotic_2017.pdf
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D'Ettorre_Probiotic-supplementation_2017.pdf
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