The growing demand of personalized medicine marked the transition from an empirical medicine to a molecular one, aimed at predicting safer and more effective medical treatment for every patient, while minimizing adverse effects. This passage has emphasized the importance of biomarker discovery studies, and has led sample availability to assume a crucial role in biomedical research. Accordingly, a great interest in Biological Bank science has grown concomitantly. In biobanks, biological material and its accompanying data are collected, handled and stored in accordance with standard operating procedures (SOPs) and existing legislation. Sample quality is ensured by adherence to SOPs and sample whole life-cycle can be recorded by innovative tracking systems employing information technology (IT) tools for monitoring storage conditions and characterization of vast amount of data. All the above will ensure proper sample exchangeability among research facilities and will represent the starting point of all future personalized medicine-based clinical trials.

Ensuring sample quality for biomarker discovery studies - Use of ict tools to trace biosample life-cycle / Riondino, Silvia; Ferroni, Patrizia; Spila, Antonella; Alessandroni, Jhessica; D'Alessandro, Roberta; Formica, Vincenzo; Della Morte, David; Palmirotta, Raffaele; Nanni, Umberto; Roselli, Mario; Guadagni, Fiorella. - In: CANCER GENOMICS & PROTEOMICS.. - ISSN 1109-6535. - STAMPA. - 12:6(2015), pp. 291-300.

Ensuring sample quality for biomarker discovery studies - Use of ict tools to trace biosample life-cycle

NANNI, Umberto;
2015

Abstract

The growing demand of personalized medicine marked the transition from an empirical medicine to a molecular one, aimed at predicting safer and more effective medical treatment for every patient, while minimizing adverse effects. This passage has emphasized the importance of biomarker discovery studies, and has led sample availability to assume a crucial role in biomedical research. Accordingly, a great interest in Biological Bank science has grown concomitantly. In biobanks, biological material and its accompanying data are collected, handled and stored in accordance with standard operating procedures (SOPs) and existing legislation. Sample quality is ensured by adherence to SOPs and sample whole life-cycle can be recorded by innovative tracking systems employing information technology (IT) tools for monitoring storage conditions and characterization of vast amount of data. All the above will ensure proper sample exchangeability among research facilities and will represent the starting point of all future personalized medicine-based clinical trials.
2015
Biobanking; Biomarker discovery; ICT tools; Review; Sample quality; Biochemistry; Molecular Biology; Genetics; Cancer Research
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Ensuring sample quality for biomarker discovery studies - Use of ict tools to trace biosample life-cycle / Riondino, Silvia; Ferroni, Patrizia; Spila, Antonella; Alessandroni, Jhessica; D'Alessandro, Roberta; Formica, Vincenzo; Della Morte, David; Palmirotta, Raffaele; Nanni, Umberto; Roselli, Mario; Guadagni, Fiorella. - In: CANCER GENOMICS & PROTEOMICS.. - ISSN 1109-6535. - STAMPA. - 12:6(2015), pp. 291-300.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/951226
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