Introduction Glioblastoma multiforme is the most aggressive type of primary brain tumors, but there is a small percentage of patients who have a long-term survival and some exceptional cases who survive decades after surgical removal of tumor. Presentation of case In 1994, a 44 year-old man, suffering from intense headache and loss of strength of the left arm, was operated for a glioblastoma multiforme in the posterior part of the right frontal lobe. After the operation the patient underwent whole-brain radiotherapy and chemotherapy. 22 years after surgery the patient has no recurrence of the tumor. Discussion A very small percentage of glioblastoma cases showed >3 years survival. There have been exceptional cases of long-survival spanning 10 years or more, without tumor recurrence, so as to deem those affected ‘cured’. The long-survival for glioblastoma multiforme is linked to young age, to aggressive and complete surgical excision, a good Karnofsky index score before surgery, the application of radiotherapy after surgery and to the molecular make-up of a specific glioma. Conclusion The fact that there are extremely rare cases of long-term survival and even zero recurrence of the glioblastoma should serve as a stimulus to continue the research effort and not give up the fight against this tumor on a day-to-day basis.

A very rare case report of long-term survival: A patient operated on in 1994 of glioblastoma multiforme and currently in perfect health / Caruso, Riccardo; Pesce, Alessandro; Wierzbicki, Venceslao. - In: INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS. - ISSN 2210-2612. - ELETTRONICO. - 33:(2017), pp. 41-43. [10.1016/j.ijscr.2017.02.025]

A very rare case report of long-term survival: A patient operated on in 1994 of glioblastoma multiforme and currently in perfect health

CARUSO, Riccardo;PESCE, ALESSANDRO;
2017

Abstract

Introduction Glioblastoma multiforme is the most aggressive type of primary brain tumors, but there is a small percentage of patients who have a long-term survival and some exceptional cases who survive decades after surgical removal of tumor. Presentation of case In 1994, a 44 year-old man, suffering from intense headache and loss of strength of the left arm, was operated for a glioblastoma multiforme in the posterior part of the right frontal lobe. After the operation the patient underwent whole-brain radiotherapy and chemotherapy. 22 years after surgery the patient has no recurrence of the tumor. Discussion A very small percentage of glioblastoma cases showed >3 years survival. There have been exceptional cases of long-survival spanning 10 years or more, without tumor recurrence, so as to deem those affected ‘cured’. The long-survival for glioblastoma multiforme is linked to young age, to aggressive and complete surgical excision, a good Karnofsky index score before surgery, the application of radiotherapy after surgery and to the molecular make-up of a specific glioma. Conclusion The fact that there are extremely rare cases of long-term survival and even zero recurrence of the glioblastoma should serve as a stimulus to continue the research effort and not give up the fight against this tumor on a day-to-day basis.
2017
Case report; Glioblastoma multiforme; Long-survival; Primary brain tumor; Prognostic factors; Treatment; Surgery
01 Pubblicazione su rivista::01a Articolo in rivista
A very rare case report of long-term survival: A patient operated on in 1994 of glioblastoma multiforme and currently in perfect health / Caruso, Riccardo; Pesce, Alessandro; Wierzbicki, Venceslao. - In: INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS. - ISSN 2210-2612. - ELETTRONICO. - 33:(2017), pp. 41-43. [10.1016/j.ijscr.2017.02.025]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/950376
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