The management of atherosclerotic renal artery stenosis (ARAS) in patients with hypertension has been the topic of great controversy. Major contemporary clinical trials such as the Cardiovascular Outcomes for Renal Artery lesions (CORAL) and Angioplasty and Stenting for Renal Atherosclerotic lesions (ASTRAL) have failed to show significant benefit of revascularization over medical management in controlling blood pressure and preserving renal function. We present here the implications and limitations of these trials and formulate recommendations for management of ARAS.

How to manage hypertension with atherosclerotic renal artery stenosis? / Ricco, Jean Baptiste; Belmonte, Romain; Illuminati, Giulio; Barral, Xavier; Schneider, Fabrice; Chavent, Bertrand. - In: THE JOURNAL OF CARDIOVASCULAR SURGERY. - ISSN 1827-191X. - STAMPA. - 58:2(2017), pp. 329-338. [10.23736/S0021-9509.16.09827-X]

How to manage hypertension with atherosclerotic renal artery stenosis?

ILLUMINATI, Giulio;
2017

Abstract

The management of atherosclerotic renal artery stenosis (ARAS) in patients with hypertension has been the topic of great controversy. Major contemporary clinical trials such as the Cardiovascular Outcomes for Renal Artery lesions (CORAL) and Angioplasty and Stenting for Renal Atherosclerotic lesions (ASTRAL) have failed to show significant benefit of revascularization over medical management in controlling blood pressure and preserving renal function. We present here the implications and limitations of these trials and formulate recommendations for management of ARAS.
2017
Angiography; Angioplasty,*instrumentation; Antihypertensive Agents, therapeutic use*; Atherosclerosis,complications; Atherosclerosis,diagnostic imaging; Atherosclerosis, physiopathology; Atherosclerosis, therapy*; Blood Pressure, drug effects*; Clinical Trials as Topic Endarterectomy, adverse effects; Evidence-Based Medicine; Humans Hypertension; Renovascular, diagnosis; Hypertension, Renovascular, etiology Hypertension; Renovascular, physiopathology; Hypertension, Renovascular, therapy*; Renal Artery, diagnostic imaging; Renal Artery, physiopathology; Renal Artery, surgery*; Renal Artery Obstruction, complications; Renal Artery Obstruction, diagnostic imaging; Renal Artery Obstruction, physiopathology; Renal Artery Obstruction, therapy*; Risk Factors Stents; Treatment Outcome; Vascular Grafting*,adverse effects; Vascular Patency
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
How to manage hypertension with atherosclerotic renal artery stenosis? / Ricco, Jean Baptiste; Belmonte, Romain; Illuminati, Giulio; Barral, Xavier; Schneider, Fabrice; Chavent, Bertrand. - In: THE JOURNAL OF CARDIOVASCULAR SURGERY. - ISSN 1827-191X. - STAMPA. - 58:2(2017), pp. 329-338. [10.23736/S0021-9509.16.09827-X]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/939307
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