Endoscopic submucosal dissection (ESD) is an effective technique to resect early Barrett's neoplasia and has advantages over conventional endoscopic mucosal resection (EMR) as it enables en bloc resection and accurate histopathological analysis of cancer resection margins. However, its long learning curve and higher adverse event rate has tempered its uptake in the West. We aimed to analyze the safety and efficacy of ESD when used to resect complex Barrett's neoplasia. The primary endpoint was the en bloc and R0 resection rate.
Complex early Barrett's neoplasia at 3 Western centers: European Barrett's Endoscopic Submucosal Dissection Trial (E-BEST) / Subramaniam, Sharmila; Chedgy, Fergus; Longcroft Wheaton, Gaius; Kandiah, Kesavan; Maselli, Roberta; Seewald, Stefan; Repici, Alessandro; Bhandari, Pradeep. - In: GASTROINTESTINAL ENDOSCOPY. - ISSN 0016-5107. - STAMPA. - (2017). [10.1016/j.gie.2017.01.027]
Complex early Barrett's neoplasia at 3 Western centers: European Barrett's Endoscopic Submucosal Dissection Trial (E-BEST)
MASELLI, ROBERTA;
2017
Abstract
Endoscopic submucosal dissection (ESD) is an effective technique to resect early Barrett's neoplasia and has advantages over conventional endoscopic mucosal resection (EMR) as it enables en bloc resection and accurate histopathological analysis of cancer resection margins. However, its long learning curve and higher adverse event rate has tempered its uptake in the West. We aimed to analyze the safety and efficacy of ESD when used to resect complex Barrett's neoplasia. The primary endpoint was the en bloc and R0 resection rate.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
